Results 181 to 190 of about 890,618 (298)

Universal Legal Justification: a Failed Alternative Between Calvin and Arminius

, 2012
Joseph Olstad
openalex   +1 more source

Alternative Splicing Plays a Major Role in Plant Response to Cold Temperatures [PDF]

, 2018
Jenna Gallegos
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Exploring bioactive and nutritional profiles in plant-based milk alternatives from green rice (Khao Dawk Mali 105) and its milling fractions. [PDF]

Food Chem X
Bunyatratchata A, Chumroenphat T, Taesuk N, Siriamornpun S.   +3 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Decision theoretic fuzzy modelling for product quality and design evaluation of basketballs using deck of cards strategy. [PDF]

Sci Rep
Zhu A.
europepmc   +1 more source

Assessment of the Potential of Decentralized Dinance (DeFi) as an Alternative to Traditional Financial Services in the Context of the Development of the Digital Economy and Web3

Oleksandr Manoylenko, S.S. Kuznetsova, Anton O. Pysakovskyi   +2 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Hybrid optimization of WEDM control parameters for Kovar using VIKOR-AHP and R method. [PDF]

Sci Rep
Ukey K, Sahu AR, Majumder H, Ashok N, Bhowmik A.   +4 more
europepmc   +1 more source

DIXIT, Avinash K., Lawlessness and Economics: Alternative Modes of Governance

, 2010
Marisol Fonseca González-Aragón
openalex   +2 more sources