Results 191 to 200 of about 890,618 (298)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

ALTERNATIVE APPROACH TO THE UTILISATION OF BIOLOGICAL WASTE FROM WASTEWATER TREATMENT

A.M. Begakhmet, Kamshat Kulzhanova, Zh.B. Tekebayeva, Aliya Теmirbekova, Zhadyrassyn Nurbekova, Aslan Temirkhanov, Ж.М. Бекшин, Timoth Mkilima, Akhan Abzhalelov   +8 more
openalex   +2 more sources

Vendi Information Gain: An Alternative To Mutual Information For Science And Machine Learning [PDF]

Quan Dong Nguyen, Adji Bousso Dieng
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Neuroscience meets food choice: Implicit and explicit consumer responses to plant-based vs animal-based foods. [PDF]

Curr Res Food Sci
Inguscio BMS, Carcaterra G, Cherubino P, Rossi D, Madini G, Fraccascia L, Babiloni F, Cartocci G.   +7 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Human Research Protection Training Requirements: Alternatives for Community Researchers at CTSA-Funded Research Institutions. [PDF]

Ethics Hum Res
Anderson EE, Santiago A.
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Reducing the environmental impact of nitrous oxide in dentistry: a national quality improvement project. [PDF]

Br Dent J
Lyne A, Ahmad S, Ashley P.
europepmc   +1 more source

New green base for Fmoc removal in solid-phase peptide synthesis: 1,5-diazabicyclo[4.3.0]non-5-ene (DBN), a promising sustainable alternative to piperidine

Scala, Maria Carmina, Vivenzio, Giovanni, Manfra, Michele, Sala, Marina, Campiglia, Pietro   +4 more
openalex   +1 more source