Results 71 to 80 of about 1,375,365 (258)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
, 2018 Alternatives to imprisonment have turned out to be practical ways of extending and expanding the criminal justice system. Resistance to the use of penalties to correct antisocial behavior has not proved sufficient to transform either these behaviors or ...
Dores, A.
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 1998 Transcript of a public hearing held by the Commission on Structural Alternatives for the Federal Courts of Appeals held April 3, 1998 in Chicago, Illinois.
United States. Administrative Office of the United States Courts.
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The evaluation system for design alternatives in collaborative design
, 2001 The evaluation of design alternatives is an important phase for supporting design decision and for producing new design concepts, and it is repeatedly processed.
E. Lee +5 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Reflections on Forty Years of Failed Australian Climate Policy (Foreword)
, 2020 Forty years ago, I analysed Australia’s future energy alternatives in the very first issue of Social Alternatives (Lowe 1977). It then became clear that climate change was significant and would demand a new approach to energy supply and use (Lowe 1989 ...
Lowe, Ian
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
An alternative idea to an alternative technique [PDF]
European Journal of Cardio-Thoracic Surgery, 2017 GAETA, Roberto, FAMA', FAUSTO
openaire +3 more sources