Results 61 to 70 of about 1,375,365 (258)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Alternative to Alternative Schools

open access: yesEuropean Journal of Teaching and Education, 2020
The fundamental research question from which this paper is going to be - is there an alternative to alternative education? Alternative schools are in the pedagogical and didactical understanding of teaching, often far ahead of their time, sometimes too far. They offer something new and different, much better than traditional classes.
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Community Enterprises: Imagining and enacting alternatives to capitalism

open access: yes, 2007
No Full ...
Gibson-Graham, J., Cameron, Jenny
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Commission on Structural Alternatives for the Federal Courts of Appeals

open access: yes, 1997
Effective March 19, 1999 the Commission on Structural Alternatives for the Federal Courts of Appeals completed its business and ceased ...
United States. Commission on Structural Alternatives for the Federal Courts of Appeals
core  

Climate Change: Where to from here?

open access: yes, 2018
Forty years ago, I analysed Australia's future energy alternatives in the very first issue of 'Social Alternatives' (Lowe 1977). This was a few years after the 'energy crisis' of the early 1970s, so the oil price had already increased in five years from ...
Lowe, Ian
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Capitalisme sans alternatives?

open access: yes, 1994
Archivo personal de Franz Hinkelammert.Alternatives Sud, vol.
Hinkelammert, Franz J. (Franz Josef), 1931-
core   +1 more source

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