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5 perspectives on translating microphysiological systems from concept to application. [PDF]
Nat Communeuropepmc +1 more source
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The Validation and Acceptance of Alternatives to Animal Testing
Toxicology in Vitro, 1999Validation is the key to the regulatory status of alternative methods. A series of questions are put, to which answers are given, including the following: What is validation? What is meant by "relevance", "reliability" and "purpose"? Why and when is formal validation necessary? What comes before and after a formal validation study?
M, Balls, J H, Fentem
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Welcome Alternatives to Animal Testing
Genetic Engineering & Biotechnology News, 2021Gary Michelson, Aysha Akhtar
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Food and Chemical Toxicology, 2023
The development of alternative methods to animal testing has gained great momentum since Russel and Burch introduced the "3Rs" concept of Reduction, Refinement, and Replacement of animals in safety testing in 1959.
N. Reddy +3 more
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The development of alternative methods to animal testing has gained great momentum since Russel and Burch introduced the "3Rs" concept of Reduction, Refinement, and Replacement of animals in safety testing in 1959.
N. Reddy +3 more
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FDA no longer has to require animal testing for new drugs
Science, 2023Description Agency can rely on animal-free alternatives before human trials Agency can rely on animal-free alternatives before human ...
M. Wadman
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Chemical & Engineering News Archive, 2007
TESTING CHEMICALS on animals for human toxicity should be greatly reduced and can potentially be eliminated in favor of experiments using cells, cell lines, or cellular components, says a National Research Council report released last week. Advances in systems biology and methods to test cells and tissues are fundamentally changing the way scientists ...
CHERYL HOGUE, JEFF JOHNSON
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TESTING CHEMICALS on animals for human toxicity should be greatly reduced and can potentially be eliminated in favor of experiments using cells, cell lines, or cellular components, says a National Research Council report released last week. Advances in systems biology and methods to test cells and tissues are fundamentally changing the way scientists ...
CHERYL HOGUE, JEFF JOHNSON
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Animals and Alternatives in Toxicity Testing
Alternatives to Laboratory Animals, 1985Animals and alternatives in toxicity testing , Animals and alternatives in toxicity testing , کتابخانه دیجیتال جندی شاپور ...
Michael Balls +2 more
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Trend on alternative to animal testing
International Journal of Cosmetic Science, 2007For the promotion of 3R's (Reduction, Refinement and Replacement) principles of animal tests, the EU and US established the European Center for the Validation of Alternative Methods (ECVAM) and the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), respectively.
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