Results 111 to 120 of about 279,349 (317)

The expression of CTLA-4 in hepatic alveolar echinococcosis patients and blocking CTLA-4 to reverse T cell exhaustion in Echinococcus multilocularis-infected mice

open access: yesFrontiers in Immunology
Alveolar echinococcosis (AE) is a zoonotic parasitic disease caused by the infection of Echinococcus multilocularis (E. multilocularis) larvae. Cytotoxic T-lymphocyte antigen 4 (CTLA-4) produces inhibitory signals and induces T cell exhaustion, thereby ...
Yuxuan Yang   +8 more
doaj   +1 more source

Origin, evolution and biogeographic dynamics of the European rabbit (Oryctolagus cuniculus) in Southwestern Europe

open access: yesThe Anatomical Record, EarlyView.
Abstract The Pleistocene is a key period for understanding the evolutionary history and palaeobiogeography of the European rabbit (Oryctolagus cuniculus). The species was first documented in southeastern Iberia at the beginning of the Middle Pleistocene and appears to have rapidly spread throughout Southwestern Europe, where it was found in numerous ...
Maxime Pelletier
wiley   +1 more source

Solar radiation pressure augmented deorbiting from high altitude sun-synchronous orbits

open access: yes, 2012
This paper discusses the use of solar radiation pressure (SRP) augmented deorbiting to passively remove small satellites from high altitude Sun-synchronous orbits. SRP-augmented deorbiting works by deploying a light-weight reflective inflatable device to
Colombo, Camilla   +2 more
core  

Effects of intermittent exposure to hypobaria and cold on the microarchitecture and morphofunctional profile of rat gastrocnemius muscle

open access: yesThe Anatomical Record, EarlyView.
Abstract Intermittent hypobaric hypoxia (IHH) enhances oxygen transport, muscle metabolism, and cardiovascular health; however, the combined effects of hypobaria and cold are less well understood. Exposure to these stressful environmental factors, even intermittently, can affect skeletal muscle due to its plasticity, thereby altering its metabolic and ...
Garoa Santocildes   +3 more
wiley   +1 more source

Effects of different hypoxia exposure on myeloid-derived suppressor cells in mice

open access: yesExperimental and Molecular Pathology
For many people living at high altitudes for long or short periods of time, hypoxia is a challenge affecting many aspects of the body, including the immune system.
Qiying Xu   +4 more
doaj   +1 more source

Evaluation of hypoxic injuries in 7 cell lines derived from different human tissues

open access: yesDi-san junyi daxue xuebao, 2019
Objective To observe hypoxic injuries in 7 cell lines derived from different human tissues to identify a cell model that is sensitive to acute hypoxic injury. Methods Seven cell lines derived from different human tissues, namely CCD 841 CoN, GES-1, HUVEC,
FENG Lan   +4 more
doaj   +1 more source

High altitude dermatology

open access: yesIndian Journal of Dermatology, 2017
Approximately, 140 million people worldwide live permanently at high altitudes (HAs) and approximately another 40 million people travel to HA area (HAA) every year for reasons of occupation, sports or recreation. In India, whole of Ladakh region, part of Northwest Kashmir, Northern part of Sikkim and Tenga valley of Arunachal are considered inhabited ...
openaire   +3 more sources

Much more than their fangs: Macroscopic anatomy of the brain of Bothrops moojeni Hoge 1966 (Squamata, Serpentes, Viperidae)

open access: yesThe Anatomical Record, EarlyView.
Abstract Neuroanatomical research has progressed considerably in several vertebrate lineages, yet studies of reptilian brain morphology remain markedly underdeveloped. Here we provide the first description of macroscopic brain anatomy and its ontogeny in the viperid Bothrops moojeni, based on a sample of seven individuals.
Paula Araújo   +2 more
wiley   +1 more source

Altitude-dependent and -independent variations in Plasmodium falciparum prevalence in northeastern Tanzania. [PDF]

open access: yes, 2005
BACKGROUND: Effective malaria control requires information about intensity of transmission across large areas and populations. Estimates based on entomological factors lack precision and are not cost-effective to obtain.
Drakeley, Chris J   +11 more
core   +1 more source

Clade‐wide morphological and functional variation of the sauropsid columella

open access: yesThe Anatomical Record, EarlyView.
Abstract The columella (=stapes) is the middle ear bone of reptiles that transmits vibrations from the environment to the inner ear. It has been shown to exhibit extensive interspecific morphological disparity in several clades; however, its morphological variation and associated functional consequences remain poorly described.
John Peacock   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy