Results 1 to 10 of about 177,045 (257)

Channels and Transporters in Ischemic Brain Edema [PDF]

Journal of Inflammation Research
Jianping Yu,1,2,* Bozhi Zhang,1,* Xin Yang,1 Yongjun Tan,2 Yuanfeng Zhou,1 Jiexin Li,1 Xinyue Mu,3 Yu Ren,2 Li Zhou,2 Qin Yang2 1Neurology Department, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People’s Republic of China ...
Yu J, Zhang B, Yang X, Tan Y, Zhou Y, Li J, Mu X, Ren Y, Zhou L, Yang Q   +9 more
doaj   +2 more sources

Brain edema formation and therapy after intracerebral hemorrhage

Neurobiology of Disease, 2023
Intracerebral hemorrhage (ICH) accounts for about 10% of all strokes in the United States of America causing a high degree of disability and mortality. There is initial (primary) brain injury due to the mechanical disruption caused by the hematoma. There
Yingfeng Wan, Katherine G. Holste, Ya Hua, Richard F. Keep, Guohua Xi   +4 more
doaj   +3 more sources

Anlotinib treatment for refractory peritumoral brain edema in brain metastases [PDF]

Discover Oncology
Background Peritumoral brain edema (PTBE) in refractory brain metastases significantly reduces the quality of life and even threatens the lives of patients with brain metastases.
Qian Kong, Juping Zhang, Jibo Zhang, Yawei Sun, Jun Guo   +4 more
doaj   +2 more sources

Pathogenesis of Brain Edema and Investigation into Anti-Edema Drugs [PDF]

International Journal of Molecular Sciences, 2015
Brain edema is a potentially fatal pathological state that occurs after brain injuries such as stroke and head trauma. In the edematous brain, excess accumulation of extracellular fluid results in elevation of intracranial pressure, leading to impaired nerve function.
Shotaro Michinaga, Yutaka Koyama
exaly   +3 more sources

Fenofibrate alleviates the brain edema after traumatic brain injury by enhancing endothelial OXPHOS [PDF]

Redox Biology
Traumatic brain injury (TBI) frequently leads to brain edema, a life-threatening complication and a major cause of mortality and disability. Here, we report that fenofibrate (FFB), an agonist of the nuclear receptor peroxisome proliferator-activated ...
Qiyuan Feng, Yingwei Gao, Xiaokun Gu, Xinxin Zhao, Xinwen Liu, Zixuan Ma, Wenlan Qi, Zhenghui He, Yuhan Han, Jian Zhang, Wenye Wang, Zhifan Li, Daiwen Zhang, Jialin Huang, Yong Lin, Jiyuan Hui, Bayasgalan Onondari, Galbadrakh Erdenetsetseg, Qing Mao, Jiyao Jiang, Yan Zhou, Weiji Weng, Yan Zhang, Junfeng Feng   +23 more
doaj   +2 more sources

Effects of perioperative hydrogen inhalation on brain edema and prognosis in patients with glioma: a single-center, randomized controlled study [PDF]

Frontiers in Neurology
IntroductionBrain edema is a life-threatening complication that occurs after glioma surgery. There are no noninvasive and specific treatment methods for brain edema.
Fan Wu, Tao Liang, Yang Liu, Chenhui Wang, Yongxing Sun, Baoguo Wang   +5 more
doaj   +2 more sources

Ischemic brain edema: Emerging cellular mechanisms and therapeutic approaches

Neurobiology of Disease, 2023
Brain edema is one of the most devastating consequences of ischemic stroke. Malignant cerebral edema is the main reason accounting for the high mortality rate of large hemispheric strokes.
Wenxuan Han, Yang Song, Marcelo Rocha, Yejie Shi   +3 more
doaj   +1 more source

The benefit of bevacizumab therapy in patients with refractory vasogenic edema caused by brain metastasis from lung and colon cancers

Frontiers in Oncology, 2022
ObjectiveThis retrospective study investigated the efficacy of bevacizumab in refractory brain edema caused by brain metastasis from lung cancer and colon cancer.MethodsA total of 72 patients with refractory brain edema were divided into the lung cancer ...
Xuexue Bai, Meng Zhou
doaj   +1 more source

Association Between Post-procedure Cerebral Blood Flow Velocity and Severity of Brain Edema in Acute Ischemic Stroke With Early Endovascular Therapy

Frontiers in Neurology, 2022
ObjectivesWe aimed to investigate the association between post-procedure cerebral blood flow velocity (CBFV) and severity of brain edema in patients with acute ischemic stroke (AIS) who received early endovascular therapy (EVT).MethodsWe retrospectively ...
Jie Pan, Jie Pan, Huadong Wu, Tingting Wu, Yu Geng, Yu Geng, Ruozhen Yuan   +6 more
doaj   +1 more source

Hypothermia reduces glymphatic transportation in traumatic edematous brain assessed by intrathecal dynamic contrast-enhanced MRI

Frontiers in Neurology, 2022
The glymphatic system has recently been shown to clear brain extracellular solutes and can be extensively impaired after traumatic brain injury (TBI). Despite hypothermia being identified as a protective method for the injured brain via minimizing the ...
Yingnan Bai, Mingyuan Yuan, Honglan Mi, Fengchen Zhang, Xiangyu Liu, Chen Lu, Yinghui Bao, Yuehua Li, Qing Lu, Qing Lu   +9 more
doaj   +1 more source