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The roles of pleiotrophin in brain injuries: a narrative review of the literature [PDF]
Annals of MedicineBackground Pleiotrophin (PTN), a secreted multifunctional growth factor, is highly expressed in the developing brain. Recently, many studies have indicated that PTN participates in the development of brain and plays a neuroprotection after brain injury ...
Yupeng Lei +4 more
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Traumatic brain injuries [PDF]
Nature Reviews Disease Primers, 2016 Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe. Mild TBI (the least severe form) is synonymous with concussion and is typically caused by blunt non-penetrating head trauma. The trauma causes stretching and tearing of axons, which leads to diffuse axonal injury - the best-studied pathogenetic mechanism of ...
KAJ Blennow, Harvey Levin, Ann C Mckee
exaly +10 more sources
An overview of sports-mediated brain injuries and their management approaches: a narrative review
Human MovementPurpose The objective of the present study was to provide an update on the 16 sports with the highest incidence of brain injuries. Thereafter, its diagnosis, treatment, and management strategies are discussed.
Parul Grover +6 more
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Microglia and Their Promising Role in Ischemic Brain Injuries: An Update
Frontiers in Cellular Neuroscience, 2020 Ischemic brain injuries are common diseases with high morbidity, disability, and mortality rates, which have significant impacts on human health and life. Microglia are resident cells of the central nervous system (CNS).
Luting Yu +11 more
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Nature Communications, 2016 Accurate treatment of traumatic brain injuries, a leading cause of neurological disability and death in young people, is hampered by poor accumulation of drugs in the brain.
Aman P. Mann +14 more
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Seminars in Respiratory and Critical Care Medicine, 2002 Traumatic brain injury (TBI) is a serious health issue in the United States, killing 100,000 people a year and serving as a source of long-term disability for many more. It is the leading cause of death in patients under the age of 45 years. Successful management of TBI requires first an appreciation that a significant part of the neuronal injury ...
Kama, Guluma, Brian, Zink
+8 more sources
Brain Sciences, 2023 (1) Background: Cerebrospinal fluid (CSF) and blood biomarkers are emerging tools used to obtain information on secondary brain damage and to improve diagnostic and prognostic accuracy for patients with prolonged post-traumatic disorders of consciousness
Sergio Bagnato, Cristina Boccagni
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Lumbosacral Sagittal Alignment in Association to Intervertebral Disc Diseases [PDF]
Asian Spine Journal, 2014 Study DesignA cross-sectional case-control study was designed to compare the sagittal alignment of lumbosacral regions in two groups of patients suffering from low back pain, one with intervertebral disc pathologies and one without.PurposeTo evaluate the
Zohreh Habibi +4 more
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Frontiers in Neurology, 2022 BackgroundStroke is one of the most frequent causes of death and disability worldwide. It is accompanied by the impaired motor function of the upper extremities in over 69% of patients up to hemiplegia in the following 5 years in 56% of cases.
Loris Pignolo +5 more
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Biomarkers of Brain Injury: A Window on Mechanisms of Injury and Recovery in the Brain
Brain Sciences, 2022 The decision-making process regarding management after severe acute brain injury is based on clinical evaluation and depends on the injury etiology as well as radiological and neurophysiological data [...]
Sergio Bagnato
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