Results 41 to 50 of about 484,647 (304)

Microglia and Their Promising Role in Ischemic Brain Injuries: An Update

open access: yesFrontiers in Cellular Neuroscience, 2020
Ischemic brain injuries are common diseases with high morbidity, disability, and mortality rates, which have significant impacts on human health and life. Microglia are resident cells of the central nervous system (CNS).
Luting Yu   +11 more
doaj   +1 more source

Children's brain injury : a postal follow-up of 525 children from one health region in the UK [PDF]

open access: yes, 2002
Primary objectives: to follow-up a population of children admitted to one Hospital Trust with traumatic brain injury (TBI), and compare outcomes following mild TBI with outcomes following moderate or severe TBI.
Hawley, Carol   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Concussion management in soccer

open access: yesJournal of Sport and Health Science, 2014
Brain injuries in sports drew more and more public attentions in recent years. Brain injuries vary by name, type, and severity in the athletic setting. It should be noted, however, that these injuries are not isolated to only the athletic arena, as non ...
Jason P. Mihalik   +3 more
doaj   +1 more source

The epidemiology of traumatic brain injuries in northeastern Iran [PDF]

open access: yesPayesh, 2023
Objective(s): Traumatic brain injuries are one of the most important causes of deaths and disabilities worldwide. This study was an epidemiological investigation of traumatic brain injuries in northeastern Iran.
Bahareh Payvar   +4 more
doaj  

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination. [PDF]

open access: yes, 2011
Permanent damage to white matter tracts, comprising axons and myelinating oligodendrocytes, is an important component of brain injuries of the newborn that cause cerebral palsy and cognitive disabilities, as well as multiple sclerosis in adults. However,
Baranzini, Sergio E   +11 more
core   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Diet-microbiome-gut-brain nexus in acute and chronic brain injury

open access: yesFrontiers in Neuroscience, 2022
In recent years, appreciation for the gut microbiome and its relationship to human health has emerged as a facilitator of maintaining healthy physiology and a contributor to numerous human diseases.
Maria Alexander Krakovski   +9 more
doaj   +1 more source

Traumatic Brain Injury Screening Tools in Primary Care [PDF]

open access: yes, 2017
Traumatic brain injuries are a significant health concern, being responsible for over 52,000 deaths each year. Unfortunately, many traumatic brain injuries often go misdiagnosed or undiagnosed. Primary care providers are the principal and first source of
Bizon Jr, Lee John
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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