Neurofilament light chain (NfL), released during central nervous injury, has evolved as a powerful serum marker of disease severity in many neurological disorders, including infectious diseases.
Chi Ho Wai +13 more
doaj +1 more source
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats [PDF]
Several studies suggest that cyclooxygenase (COX)-2 plays a pivotal role in the progression of ischemic brain damage. In the present study, we investigated the effects of selective inhibition of COX-2 with nimesulide (12 mg/kg) and selective inhibition ...
Candelario-Jalil, Eduardo +4 more
core +2 more sources
Background: Brain edema induced by radiotherapy is a common complication in patients with brain tumors, for which medical treatment is the treatment of choice.
Da-Tong Ju +4 more
doaj +1 more source
Pengaruh Ramipril Terhadap Gambaran Histopatologis Otak Tikus Wistar yang Mengalami Edema Otak
Background. Brain edema is excessive accumulation of fluid in the intracranial or extracellular space of the brain. It can be caused by head trauma, brain tumors, hypoxia, metabolic disorders, or acute hypertension.
Rizka Fitria Husni +2 more
doaj +1 more source
Immunohistochemical evaluation of aquaporin-4 and its correlation with CD68, IBA-1, HIF-1α, GFAP, and CD15 expressions in fatal traumatic brain injury [PDF]
Traumatic brain injury (TBI) is one of the leading causes of death and disability worldwide. Our understanding of its pathobiology has substantially increased.
Cantatore, Santina +13 more
core +2 more sources
Peritumoral edema in meningiomas: a review of influencing factors, mechanisms, and management
Peritumoral brain edema is an accompanying symptom of meningiomas, and its severity impacts patient symptoms and prognosis. Meningioma-related peritumoral brain edema can result in severe symptoms such as neurological disturbance and brain herniation ...
Gaocai Zhang +6 more
doaj +1 more source
Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke. [PDF]
Numerous studies have documented increases in matrix metalloproteinases (MMPs), specifically MMP-9 levels following stroke, with such perturbations associated with disruption of the blood brain barrier (BBB), increased risk of hemorrhagic complications ...
Adibhatla +133 more
core +3 more sources
Pseudo-subarachnoid hemorrhage sign associated with severe cerebral edema
Background: A 34-year-old caucasian male underwent laparoscopic gastric bypass. The procedure was complicated by leakage and secondary peritonitis with subsequent shock and diffuse intravascular coagulation. He underwent re-intervention with splenectomy,
B De Keyzer +3 more
doaj +1 more source
Numerical characterization of intraoperative and chronic electrodes in deep brain stimulation [PDF]
An intraoperative electrode (microelectrode) is used in the deep bra In stImulation (DBS) technique to pinpoint the brain target and to choose the best parameters for the electrical stimulus.
Apollonio, Francesca +4 more
core +2 more sources
Acute hydrogen sulfide-induced neuropathology and neurological sequelae: challenges for translational neuroprotective research. [PDF]
Hydrogen sulfide (H2 S), the gas with the odor of rotten eggs, was formally discovered in 1777, over 239 years ago. For many years, it was considered an environmental pollutant and a health concern only in occupational settings. Recently, however, it was
Anantharam, Poojya +4 more
core +1 more source

