Results 101 to 110 of about 72,692 (245)

VERMONT μQFR: Diagnostic Accuracy of Murray Law‐Based 2D‐μQFR Compared to 3D‐μQFR and vFFR

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Murray law‐based quantitative flow ratio (μQFR) is an angiography‐derived physiological index that utilizes a single angiographic projection with artificial intelligence‐guided vessel segmentation. Aims To evaluate the diagnostic accuracy and time efficacy of 2D‐μQFR against wire‐based fractional flow reserve (FFR ≤ 0.80), compare ...
Daniel Akrawi   +16 more
wiley   +1 more source

Validation of an Automated Artificial Intelligence‐Driven Planner for Transcatheter Aortic Valve Replacement

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Preprocedural planning with multislice computed tomography (MSCT) is an essential prerequisite for successful transcatheter aortic valve replacement (TAVR). However, preprocedural planning is time‐consuming and may contain clinically meaningful interobserver variability.
Mark M. P. van den Dorpel   +11 more
wiley   +1 more source

pH Determination in Grape Must by Benchtop NMR Spectroscopy

open access: yesChemFoodChem, EarlyView.
Benchtop NMR spectroscopy enables electrode‐free pH determination in grape must. By modeling tartaric acid's chemical shift variation, pH is derived directly from NMR spectra alongside standard composition parameters. Validated against 100 samples, this integrated approach tracks pH changes during acidification, deacidification, and fermentation ...
Billy Salgado   +9 more
wiley   +1 more source

A letter from Sidney Altman to Colleagues at Yale College, announcing the appointment of Mary Romero as Assistant Dean at Yale College.

open access: yes, 1985
A letter from Sidney Altman, Dean of Yale College to Colleagues at Yale College, announcing the appointment of Mary Romero as Assistant Dean at Yale ...
Altman, Sidney
core   +4 more sources

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang   +2 more
wiley   +1 more source

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke   +12 more
wiley   +1 more source

Plebiscitos, referendos e iniciativas populares en América Latina / Plebiscits, Referendums and Popular Initiatives in Latin America

open access: yesPerfiles Latinoamericanos, 2010
En este artículo se estudian y ordenan las diferentes formas con que la ciudadanía decide directamente en las urnas sobre temas de su incumbencia. La apelación directa a la ciudadanía parece cada día más de moda en la región, cuestión que muchos autores ...
David Altman
doaj  

Creatinine–Cystatin C Discrepancy and Renal Transporter Polymorphisms in Japanese Patients with Breast Cancer Receiving Abemaciclib

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Abemaciclib increases serum creatinine by inhibiting renal tubular transporters rather than reducing true glomerular filtration rate, a phenomenon known as pseudo‐acute kidney injury. Creatinine–cystatin C discrepancy and genetic determinants of this elevation remain insufficiently characterized in Japanese patients.
Hiroaki Watanabe   +5 more
wiley   +1 more source

Ethical Behaviour and Corporate Financing. The Case of ‘Legality Rating’

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The financial crisis has heightened awareness of ethical and legal issues in the business context. Corporate ethical behaviour is increasingly measured through sustainability ratings. Since 2012, in Italy, the introduction of a sustainability rating, namely the legality rating (LR), has served as an innovative ‘label’ for socially responsible ...
Federica Doni   +3 more
wiley   +1 more source

Dynamic Games in Novel Networks: Guest Editors' Forewords

open access: yes, 2016
An increasing number of man-made networked systems, such as social networks and online platforms, govern the interactions between players through predefined actions such as the possibility of sharing informations, accessing a service, express opinions or
Altman, E., De Pellegrini, Francesco
core   +1 more source

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