Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla +15 more
wiley +1 more source
Enhancement of the Phase Transition Enthalpy of an Organic Phase Change Material Through the Use of Clinoptilolite. [PDF]
Musiał M +3 more
europepmc +1 more source
Highly Entangled Bottlebrush Polymer Networks
Bottlebrush polymers are difficult to entangle, enabling ultrasoft yet brittle networks. We report highly entangled bottlebrush elastomers that remain ultrasoft (∼1 kPa) yet stretch to ∼1800% and exhibit exceptional fatigue resistance. Their intrinsic fatigue strength—fatigue threshold normalized by modulus—surpasses that of highly entangled linear ...
Myoeum Kim +3 more
wiley +1 more source
Preparation of Boron Nitride Nanotube/Aluminum Matrix Composites and Their Application in Automotive Connecting Rods. [PDF]
Huang Y, Zhang B, Zhao H, Li Q, Bi J.
europepmc +1 more source
A Geometrically Transient Platform for Bioelectronic Implants
Minimally invasive bioelectronic implants often compromise performance for smaller sizes. To resolve this optimization dilemma, a wireless bioelectronic implant with a transient geometry is introduced (MiFi). The origami‐inspired device miniaturizes up to sixfold for syringe insertion and autonomously unfolds post‐implantation.
Selin Olenik +13 more
wiley +1 more source
Green preparation and evaluation of bentonite supported Bi<sub>2</sub>O<sub>3</sub>/polyester nanocomposites as gamma radiation shielding materials. [PDF]
Hamada MA +5 more
europepmc +1 more source
We reveal the electronic origin of hidden interfacial doping in monolayer MoS2 grown by MOCVD, identifying sulfate related and water like species as intrinsic donors. Through dry interface engineering approach, we demonstrate MOCVD‐grown single‐crystal MoS2 wafers as a transfer‐free platform for the reliable evaluation of intrinsic gate stacks and ...
Shuhong Li +12 more
wiley +1 more source
Sustainable assessment of process-reinforcement interaction effects on mechanical strength of FSW Al 7475 hybrid composites. [PDF]
Budavarthi IB +7 more
europepmc +1 more source
Microstructure and mechanical properties of aluminium-aluminium carbide composites
openaire +1 more source
Meniscus‐Guided Interfacial Ring‐by‐Ring Assembly for In Situ Fabrication of Tubular Hydrogels
A tubular hydrogel fabrication method leveraging the meniscus effect at the oil‐water interface is presented. UV irradiation across the concave surface of the photocurable hydrogel precursor induces the formation of ring‐like hydrogel structures. Sequential ring‐by‐ring assembly within microchannels enables the construction of arteriole‐scale hydrogel ...
Yuki Kamiya +2 more
wiley +1 more source

