Results 61 to 70 of about 3,529,436 (296)

Avaliação das alterações dentárias imediatas à expansão maxilar com o aparelho quadrihélice por meio de tomografia computadorizada de feixe cônico [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2013.Objetivo: Avaliar as alterações dentárias imediatas de inclinação, altura e espessura alveolar na ...
Floriano, Gilberto
core  

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning

Advanced Science, EarlyView.
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley   +1 more source

Neuropeptide Y—Graphene Oxide Complexes Inhibit Amygdala NPY‐Receptor Expressing Glutamatergic Pathways and Selectively Remove Aversive Memory In Vivo

Advanced Science, EarlyView.
A graphene oxide nanocarrier presents neuropeptide Y specifically to NPY receptor‐expressing pathways in the amygdala, whose activation selectively suppresses aversive memory formation, without modulating anxiety responses. This circuit‐restricted drug release strategy may impact future design of neuropsychiatric therapies with limited off‐target ...
Elisa Pati, Audrey Franceschi Biagioni, Raffaele Casani, Luis M. Arellano, Tommaso Battisti, Gloria Garcia‐Ortega, Neus Lozano, Alberto Bianco, Kostas Kostarelos, Laura Ballerini, Giada Cellot   +10 more
wiley   +1 more source

Enxerto ósseo tipo autógeno em maxilares atróficos [PDF]

, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Rebordos alveolares severamente reabsorvidos nos maxilares atróficos tem sido um problema na reabilitação protética dos pacientes, tanto para colocação de
Pereira, José Augusto de Bem
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Experimentally induced alveolar bone loss.

, 2015
Buccal view of mandibular left molars in (A) control mouse (CMC inoculations); (B) experimental mouse (P. gingivalis and F. nucleatum inoculations). Observable alveolar bone loss in (B) compared with (A) as indicated by the distance from the cemento ...
Claire T. Roberts (103366), Tracy R. Fitzsimmons (711319), Ceilidh Marchant (588068), Sara Stockham (711317), P. Mark Bartold (711320), Peter S. Zilm (711321), Justine E. Stamford (711318)   +6 more
core   +1 more source

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

Comparison of Diagnostic Accuracy of Conventional Intraoral Periapical and Direct Digital Radiographs in Detecting Interdental Bone Loss [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: Periodontitis is an inflammatory disease of the supporting tissues of the teeth caused by specific microorganisms, resulting in destruction of the periodontal ligament and alveolar bone.
Ashwinirani S.R., Girish Suragimath, Jaishankar H.P., Prasad Kulkarni, Shobha C. Bijjaragi, Varsha Ajit Sangle   +5 more
doaj   +1 more source

Synergistic effect of photodynamic therapy and alendronate on alveolar bone loss in rats with ligature-induced periodontitis

, 2017
Background and Objective: Photodynamic therapy (PDT) and antiresorptive drugs, such as alendronate (ALN), have been shown to reduce alveolar bone loss. The aim of this study was to evaluate the possible synergic effects of combining PDT and ALN on bone ...
F. Camacho-Alonso, Martínez Beneyto, Yolanda, Tudela-Mulero, M.R., Merino, J.J:, Tudela-Mulero, María del Rosario, C. Vilaplana-Vivo, Y. Martínez-Beneyto, R. S. Davia-Peña, Camacho Alonso, Fabio, M. R. Tudela-Mulero, Vilaplana-Vivo, Carlos, Vilaplana-Vivo, C., Davia Peña, R.S., Merino Martín, José Joaquín, Martínez-Beneyto, Yolanda, Davia-Peña, Roque Samuel, Camacho-Alonso, Fabio, J. J. Merino   +17 more
core   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source