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Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis. [PDF]
An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Ou Z +35 more
europepmc +2 more sources
Hepatic alveolar echinococcosis (HAE) is a zoonotic parasitic disease caused by the larvae of Echinococcus multilocularis. Because of its characteristics of diffuse infiltration and growth similar to tumors, the disability rate and mortality rate are ...
Xiaolei Xu +37 more
doaj +1 more source
Epidemic cystic and alveolar echinococcosis in Kyrgyzstan: an analysis of national surveillance data
Summary: Background: Human cystic and alveolar echinococcosis are among the priority neglected zoonotic diseases for which WHO advocates control. The incidence of both cystic echinococcosis and alveolar echinococcosis has increased substantially in the ...
Giulia Paternoster, DVM +12 more
doaj +1 more source
Hepatic alveolar echinococcosis [PDF]
A 79-year old female patient with past history of breast adenocarcinoma underwent an abdominal computed tomography (CT) for asthenia and nausea.
Jean Delwaide +9 more
openaire +2 more sources
Background Human cystic and alveolar echinococcosis are neglected tropical diseases that WHO has prioritized for control in recent years. Both diseases impose substantial burdens on public health and the socio-economy in China.
Tian Ma +21 more
doaj +1 more source
Background The organ most commonly invaded in echinococcosis is the liver; the lungs, brain, kidneys, heart, and spleen are rarely invaded, and multi-organ involvement in echinococcosis is even rarer.
Qirui Hu +5 more
doaj +1 more source
Isolated Cerebral Alveolar Echinococcosis [PDF]
Abstract Cerebral alveolar echinococcosis (AE) is rare and mostly associated with liver involvement. We report an exceptional case of a 62-year-old man with a hereditary hemorrhagic telangiectasia harboring a primary cerebral AE mimicking neurocysticercosis with >100 cerebral lesions and without liver involvement.
Baldolli, Aurélie +7 more
openaire +5 more sources
Alveolar echinococcosis in immunocompromised hosts
Alveolar echinococcosis (AE) results of an infection with the larval stage of Echinococcus multilocularis. It has been increasingly described in individuals with impaired immune responsiveness.This narrative review aims at describing the presentation of AE according to the type of immune impairment, based on retrospective cohorts and case reports ...
Autier, Brice +7 more
openaire +4 more sources
Morphological Characteristics of Alveolar and Cystic Echinococcosis Lesions in Human Liver and Bone
Among echinococcoses diseases of human interest, two have a global public health impact: cystic and alveolar echinococcosis caused by Echinococcus granulosus sensu lato and Echinococcus multilocularis, respectively. Cystic and alveolar echinococcosis are
Thomas F. E. Barth, Adriano Casulli
doaj +1 more source

