Results 1 to 10 of about 7,740 (174)

CircAFF1 Is a Circular RNA with a Role in Alveolar Rhabdomyosarcoma Cell Migration [PDF]

Biomedicines, 2023
Circular RNAs (circRNAs), covalently closed RNAs that originate from back-splicing events, participate in the control of several processes, including those that occur in the development of pathological conditions such as cancer.
Alessio Colantoni, Alvaro Centrón-Broco, Irène Bozzoni   +2 more
exaly   +4 more sources

Therapeutic targeting of ATR in alveolar rhabdomyosarcoma [PDF]

Nature Communications, 2022
Alveolar rhabdomyosarcoma is a clinically challenging disease due to the lack of druggable targets. Here the authors show preclinical evidence for ATR inhibitors as a therapeutic option for alveolar rhabdomyosarcoma.
Heathcliff Dorado García, Fabian Pusch, Yi Bei, Jennifer von Stebut, Glorymar Ibáñez, Kristina Guillan, Koshi Imami, Dennis Gürgen, Jana Rolff, Konstantin Helmsauer, Stephanie Meyer-Liesener, Natalie Timme, Victor Bardinet, Rocío Chamorro González, Ian C. MacArthur, Celine Y. Chen, Joachim Schulz, Antje M. Wengner, Christian Furth, Birgit Lala, Angelika Eggert, Georg Seifert, Patrick Hundsoerfer, Marieluise Kirchner, Philipp Mertins, Matthias Selbach, Andrej Lissat, Frank Dubois, David Horst, Johannes H. Schulte, Simone Spuler, Daoqi You, Filemon Dela Cruz, Andrew L. Kung, Kerstin Haase, Michela DiVirgilio, Monika Scheer, Michael V. Ortiz, Anton G. Henssen   +38 more
doaj   +2 more sources

Generation of an iPSC-derived alveolar rhabdomyosarcoma cell line during directed endothelial differentiation [PDF]

Stem Cell Research
Alveolar rhabdomyosarcoma (ARMS) is an aggressive soft tissue sarcoma typically driven by the oncofusion protein PAX3::FOXO1 (P3F). Despite ARMS tumor histology and transcriptome resembling skeletal muscle, these tumors arise in areas devoid of skeletal ...
Randolph K. Larsen, IV, Madeline B. Searcy, Bradley T. Stevens, Katherine E. Gadek, Yang Zhang, Brian J. Abraham, Mark E. Hatley   +6 more
doaj   +2 more sources

First Description of Alveolar Rhabdomyosarcoma of the Larynx in a Young Child

Ear, Nose and Throat Journal, 2022
Rhabdomyosarcoma of the larynx has been very rarely described in pediatric population. There are 3 histological subtypes: embryonal, pleomorphic, and alveolar.
Julien Quere, Marianowski Rémi, Jean-Christophe Leclere   +2 more
exaly   +2 more sources

Primary alveolar rhabdomyosarcoma of the brain: a case report [PDF]

Journal of Medical Case Reports
Background Primary brain rhabdomyosarcoma is a rare primary brain malignancy with few case reports. The vast majority of cases of primary brain rhabdomyosarcoma occur in pediatric patients, and immunohistochemistry can distinguish it from embryonal ...
Layal Al Mahmasani, Marwan Najjar, Roula Hourany, Abeer Tabbarah, Sara Sinno, Nathalie Chamseddine, Reine Abou Zeidane, Ghid Amhaz, Bassem Youssef, Hazem I. Assi   +9 more
doaj   +2 more sources

Case report: Lymph node metastasis of pelvic alveolar rhabdomyosarcoma diagnosed by fine needle aspiration cytology [PDF]

Frontiers in Oncology
Rhabdomyosarcoma (RMS) is a common soft tissue malignant tumor, especially in young patients. Alveolar rhabdomyosarcoma (ARMS) is a subtype of RMS that is prevalent in adolescents.
Xinyu Hu, Chenxin Huang, Qiyuan Li, Baolin Wu, Chuyun Yue, Xueying Su   +5 more
doaj   +2 more sources

Metastatic Alveolar Rhabdomyosarcoma with Extensive Bone Marrow Replacement in an Older Adult

Case Reports in Oncology, 2021
Rhabdomyosarcoma is extremely rare in adults. Metastatic rhabdomyosarcoma can resemble other malignancies, which can delay diagnosis and prompt treatment.
Justin J. Cheng, Ryan T. Mott, Paul D. Savage, Ravi K. Paluri   +3 more
doaj   +1 more source

Proton beam therapy in paediatric cancer: Anticipating the opening of the Australian Bragg Centre for Proton Therapy and Research

Journal of Medical Imaging and Radiation Oncology, EarlyView., 2023
Summary Proton Beam Therapy (PBT) has the potential to improve paediatric cancer care by reducing radiation exposure and thus long‐term toxicities. Ethical concerns and debates surrounding the treatment, such as eligibility and accessibility, are ongoing in Australia. The Australian Bragg Centre for Proton Therapy and Research (ABCPTR) (named after Sir
Jeremy Khong, Hui Tee, Peter Gorayski, Hien Le, Michael Penniment, Sophie Jessop, Jordan Hansford, Melanie Penfold, Julia Green, Kelly Skelton, Frank Saran   +10 more
wiley   +1 more source

Surgical approach and prognosis of primitive chest wall alveolar rhabdomyosarcoma in an adult: A case report and review of the literature [PDF]

Journal of Clinical and Investigative Surgery, 2020
Alveolar rhabdomyosarcomas (ARMS) are rare entities that occur predominantly on the extremities and represent 20% of rhabdomyosarcomas. Other common locations include the peri-rectal and perineal regions, head and neck, and genitourinary system.
Razafimanjato, Narindra Njarasoa Mihaja, Ravelomihary, Tsiry Dama Ntsoa, Ranaivomanana, Mampionona, Tsiambanizafy, Guillaume Odilon, Rakotovao, Hanitrala Jean Louis, Hunald, Francis Allen   +5 more
doaj   +1 more source

Breast metastasis in an adult woman with alveolar rhabdomyosarcoma of the ethmoid sinus

Radiology Case Reports, 2014
A new breast mass was identified in an adult woman undergoing treatment for a known ethmoid sinus alveolar rhabdomyosarcoma. Histopathological evaluation revealed alveolar rhabdomyosarcoma metastatic to the breast.
Sean D. Raj, MD, Karuna M. Raj, MD, Savitri Krishnamurthy, MD, Ashrita Brahmaroutu, Gary J. Whitman, MD   +4 more
doaj   +1 more source