Results 11 to 20 of about 7,740 (174)
NFκB signaling in alveolar rhabdomyosarcoma [PDF]
Disease Models & Mechanisms, 2017 Alveolar rhabdomyosarcoma (aRMS) is a pediatric soft tissue cancer commonly associated with a chromosomal translocation that leads to the expression of a Pax3:Foxo1 or Pax7:Foxo1 fusion protein, the developmental underpinnings of which may give clues to ...
Megan M. Cleary +8 more
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Leukaemic alveolar rhabdomyosarcoma [PDF]
British Journal of Haematology, 2010 A 13-year-old previously well girl presented with a five-week history of lethargy, loss of weight and left upper quadrant pain radiating to her thoracolumbar spine. Examination revealed pallor, left upper quadrant tenderness and bilateral lower limb weakness with brisk lower limb and extensor plantar reflexes together with bilateral clonus.
Sarah, Curry +4 more
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Parameningeal alveolar rhabdomyosarcoma in a child. [PDF]
BMJ Case Rep, 2021 This is the case of a parameningeal alveolar rhabdomyosarcoma (ARMS) in a 13-year-old boy who presented with painless loss of vision in the right eye, but very few other physical signs. The ARMS diagnosis was confirmed with imaging and molecular characterisation of the tumour. Despite tolerating the initial chemotherapy and radiotherapy regimens, there
Kumar A, Pothula V.
europepmc +3 more sources
SMARCA4 biology in alveolar rhabdomyosarcoma. [PDF]
Oncogene, 2022 Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and phenocopies a muscle precursor that fails to undergo terminal differentiation. The alveolar subtype (ARMS) has the poorest prognosis and represents the greatest unmet medical need for RMS. Emerging evidence supports the role of epigenetic dysregulation in RMS.
Bharathy N +22 more
europepmc +5 more sources
Rare Adult Subtype of Rhabdomyosarcoma, a Common Childhood Soft Tissue Carcinoma
Journal of Investigative Medicine High Impact Case Reports, 2021 Rhabdomyosarcoma is a malignant soft tissue sarcoma of primitive mesenchymal cells, showing varying degrees of striated skeletal muscle cell differentiation. It is a very common cancer of childhood and adolescence, but rarely seen in the adult population.
Manasa Dondapati MS3 +4 more
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Postauricular congenital alveolar rhabdomyosarcoma- a case report of an unusual entity
Diagnostic Pathology, 2006 Background Congenital alveolar rhabdomyosarcoma is an extremely uncommon and invariably fatal tumor with the current therapy. Less than 25% of patients present with evidence of cutaneous metastasis.
Rao Narasimhan KL +2 more
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“Juvenile alveolar rhabdomyosarcoma of mandible” [PDF]
Indian Journal of Otolaryngology and Head and Neck Surgery, 1999 Rhabdomyomatous tumours are the malignant neoplasms of complex composition and deriva-tion. Three varities of Rhabdomyosarcoma are described. These are -1. Pleomorphic 2. Embryonal 3. AlveolarJuvenile Alveolar Rhabdomyosarcoma usually affects extremities and less commonly trunk, or-bit, soft tissues of the face (Cheek), Neck and oral cavity including ...
A K, Saxena, A, Singhal
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MUC4 is expressed in alveolar rhabdomyosarcoma. [PDF]
Histopathology, 2021 AimsMucin 4 (MUC4) is a transmembrane glycoprotein normally expressed by several human epithelial surfaces, including those of the colon, vagina, and respiratory tract. Although MUC4 overexpression is seen in various carcinomas, its expression among mesenchymal neoplasms is fairly specific to low‐grade fibromyxoid sarcoma and sclerosing epithelioid ...
Forgó E, Hornick JL, Charville GW.
europepmc +3 more sources
Urology Case Reports, 2022 We report a case of alveolar rhabdomyosarcoma of the bladder which achieved complete response with neoadjuvant chemotherapy and surgery. A 58-year-old man was referred to our hospital due to bladder tumor discovered with urinary frequency and gross ...
Ayato Ito +5 more
doaj +1 more source