Results 31 to 40 of about 1,879 (171)

Pediatric hypersensitivity pneumonitis: literature update and proposal of a diagnostic algorithm

open access: yesItalian Journal of Pediatrics, 2022
Hypersensitivity pneumonitis (HP) is a rare disease in childhood with the prevalence of 4 cases per 1 million children and an incidence of 2 cases per year. The average age of diagnosis at pediatric age is approximately 10 years.
Carla Mastrorilli   +12 more
doaj   +1 more source

Protein kinase D1 in myeloid lineage cells contributes to the accumulation of CXCR3+CCR6+ nonconventional Th1 cells in the lungs and potentiates hypersensitivity pneumonitis caused by S. rectivirgula. [PDF]

open access: yesFront Immunol
IntroductionHypersensitivity pneumonitis (HP) is an extrinsic allergic alveolitis characterized by inflammation of the interstitium, bronchioles, and alveoli of the lung that leads to granuloma formation.
Snyder JD   +5 more
europepmc   +2 more sources

Agricultural Occupational Health Knowledge and Practice of Farmers in 2007 in Qom Province [PDF]

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2007
Background and objectives: Occupational health is a very important issue in all sectors, and particularly, agriculture. Agriculture is a potentially hazardous industry associated with many occupational injuries and illnesses.
K. Heidari, S. M. H. Razavi Asl
doaj   +2 more sources

Aspergillus-Related Lung Disease

open access: yesCanadian Respiratory Journal, 2005
Aspergillus is a ubiquitous dimorphic fungus that causes a variety of human diseases ranging in severity from trivial to life-threatening, depending on the host response.
Alia Al-Alawi   +3 more
doaj   +1 more source

Co-modulation of T cells and B cells enhances the inhibition of inflammation in experimental hypersensitivity pneumonitis

open access: yesRespiratory Research, 2022
Background Hypersensitivity pneumonitis (HP) is an interstitial lung disease characterized by antigen-triggered neutrophilic exacerbations. Although CD4+ T cells are sufficient for HP pathogenesis, this never translated into efficient T cell-specific ...
Olivier Courtemanche   +8 more
doaj   +1 more source

Telomerase modRNA Offers a Novel RNA‐Based Approach to Treat Human Pulmonary Fibrosis

open access: yesAging Cell, Volume 24, Issue 11, November 2025.
Recombinant linear and circular hTERT mRNA restore telomerase activity in primary ATII cells and ex vivo lung tissue from patients with pulmonary fibrosis, leading to telomere elongation, reduced DNA damage, and decreased senescence and fibrosis markers.
Jia Li Ye   +14 more
wiley   +1 more source

BN 52021 (a platelet activating factor-receptor antagonist) decreases alveolar macrophage-mediated lung injury in experimental extrinsic allergic alveolitis

open access: yesMediators of Inflammation, 1998
Several lines of research indirectly suggest that platelet activating factor (PAF) may intervene in the pathogenesis of extrinsic allergic alveolitis (EAA).
J-L. Pérez-Arellano   +5 more
doaj   +1 more source

Comorbidities and survival in patients with chronic hypersensitivity pneumonitis

open access: yesRespiratory Research, 2020
Introduction Chronic Hypersensitivity Pneumonitis (cHP) is a fibrotic interstitial lung disease (ILD) resulting from repeated exposure to an offending antigen.
Julia Wälscher   +6 more
doaj   +1 more source

Respiratory Ill‐Health and Welding Exposures: A Canadian Cohort Study

open access: yesAmerican Journal of Industrial Medicine, Volume 68, Issue 2, Page 99-111, February 2025.
ABSTRACT Introduction Respiratory ill‐health in welders is well documented but without a clear indication of exposures responsible. Methods In a Canadian cohort study of welders and electrical workers, we collected self‐reports of asthma/wheeze and rhinitis at each 6‐monthly contact for up to 5 years.
Jean‐Michel Galarneau   +2 more
wiley   +1 more source

Diagnosis and management of hypersensitivity pneumonitis in adults: A position statement from the Thoracic Society of Australia and New Zealand

open access: yesRespirology, Volume 29, Issue 12, Page 1023-1046, December 2024.
Abstract Hypersensitivity pneumonitis (HP) is an immune‐mediated interstitial lung disease (ILD) relating to specific occupational, environmental or medication exposures. Disease behaviour is influenced by the nature of exposure and the host response, with varying degrees of lung inflammation and fibrosis seen within individuals. The differentiation of
Hayley Barnes   +15 more
wiley   +1 more source

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