Assessing the Potential to Induce Respiratory Hypersensitivity [PDF]
Toxicological Sciences, 2005 Acute and repeat dose inhalation studies have been an important part of the safety assessment of drugs, chemicals, and other products throughout the world for many years. It is known that damage to the respiratory tract can be triggered either by nonspecific irritation or by specific immune-mediated pathogenesis, and it is acknowledged that traditional
Holsapple, Michael P. +7 more
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Evaluation of a translational swine model of respiratory hypersensitivity induced by exposure to Phleum pratense pollen allergens [PDF]
Frontiers in AllergyIntroductionAsthma is a disease characterized by chronic inflammation of the airway mucosa that causes tissue remodeling and a reversible decrease in airflow.
Jessica Ledesma-Aparicio +7 more
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From respiratory viral infection to persistent cough hypersensitivity: neuroimmune regulation and therapeutic implications of P2X3/TRP ion-channel targets [PDF]
Frontiers in PharmacologyRespiratory viral infections are increasingly recognized as important drivers of persistent airway symptoms and exacerbations in chronic lung disease. Post-infectious cough (PIC), particularly after upper respiratory tract infection, represents one of ...
Borui Li +6 more
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Immediate Fluoxetine Hypersensitivity With Predominant Airway and Oropharyngeal Symptoms in an Adolescent [PDF]
Case Reports in PediatricsFluoxetine is a widely prescribed selective serotonin reuptake inhibitor in children and adolescents. Hypersensitivity reactions are rare and poorly characterized in this population.
Mariana Viegas +4 more
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Cross-Reactivity Between Halogenated Platinum Salts in an Immediate-Type Respiratory Hypersensitivity Model [PDF]
Inhalation Toxicology, 2018 David M Lehmann
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Associations of Dietary Patterns and Allergies With Asthma Among University Students in Bangladesh: A Cross‐Sectional Study [PDF]
Health Science ReportsBackground and Aims Asthma is a major public health problem worldwide, with a growing burden among young adults in low‐ and middle‐income countries, including Bangladesh.
Muslima Akter +2 more
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Frontiers in Allergy, 2023 BackgroundChronic rhinosinusitis with nasal polyps (CRSwNP) and asthma frequently co-exist and share pathologic features. Taking a “global” treatment approach benefits diagnosis and treatment of both, but care is often siloed by specialty: joined-up ...
Vibeke Backer +26 more
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The relation between nonspecific hyperreactivity of the airways and atopic constitution in asthmatics [PDF]
Vojnosanitetski Pregled, 2016 Background/Aim. Hyperreactivity of the airways caused by inflammation in asthmatics is the most important pathophysiological change. It represents a suitable ground that in the presence of risk factors and the drivers of asthma, asthmatic attack occurs ...
Novković Dobrivoje +3 more
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Symptoms, physical findings and bronchial hypersensitivity in patients with bronchial asthma and normal spirometry [PDF]
Vojnosanitetski Pregled, 2009 Background/Aim. The diagnosis of bronchial asthma, a chronic inflammatory disease of the respiratory tract, is made on the basis of anamnesis, pathologic auscultatory findings of the lungs, lung function disturbances, skin tests, as well as the basic ...
Aćimović Slobodan +6 more
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Allergic Rhinitis in Relation to Food Allergies: Pointers to future research
Sultan Qaboos University Medical Journal, 2018 Allergic rhinitis is a ubiquitous type of allergic reaction which results in significant costs to affected patients and their families. Although allergic rhinitis can coexist with other atopic conditions, the role of food allergies in the development of ...
Rashid Al-Abri +3 more
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