Results 31 to 40 of about 955,664 (289)

Nasal symptoms in patients with NSAID hypersensitivity [PDF]

Rhinology Online, 2019
Background: Approximately 1 to 2% of the general population suffers from nonsteroidal anti-inflammatory drugs (NSAID) hypersensitivity. NSAID hypersensitivity is closely associated with concomitant respiratory disease.
B. Lange, C.G. Mortz, C. Bindslev-Jensen, A.D. Kjeldsen   +3 more
doaj   +1 more source

Cough Assessment in Chronic Respiratory Diseases (COASESS): Findings from a Prospective Multicenter Cross-Sectional Study [PDF]

Tuberculosis and Respiratory Diseases
Background Cough is a prominent symptom of chronic respiratory diseases, including asthma, idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and bronchiectasis (BE).
Tai Joon An, Hyeon-Kyoung Koo, Chin Kook Rhee, Yee Hyung Kim, Sung-Kyoung Kim, Kyung Hoon Min, Deog Kyeom Kim, Jong-Wook Shin, Hyoung Kyu Yoon, Woo-Jung Song, Jin Woo Kim, Ji-Yong Moon,   +12 more
doaj   +1 more source

Anaphylaxis: the main triggers and clinical picture

Лечащий Врач, 2021
Types of anaphylaxis - severe systemic reaction of hypersensitivity characterized by rapid beginning and life-threatening problems of respiratory tracts and blood circulation – were considered. The most wide-spread triggers of this condition and clinical
I. I. Balabolkin, D. Sh. Macharadze, A. Yu. Konischeva   +2 more
doaj   +1 more source

A DNA G‐Quadruplex‐Targeting Ligand Suppresses c‐MYC Expression: Implications for Gemcitabine‑Resistant Pancreatic Cancer

Angewandte Chemie, EarlyView.
PQB‐4, a fluorescent small‐molecule ligand that targets c‐MYC DNA G‐quadruplexes (G4s), showed marked synergy with gemcitabine in resistant PANC‐1 cells (CI = 0.027). In vivo, the ligand reduced tumor weight by 44% in a PANC‐1 xenograft model. These results highlight the therapeutic potential of c‐MYC DNA G4‐targeting ligands for treating gemcitabine ...
Bo‐Xin Zheng, Ya‐Kun Wang, Ze‐Xin Chen, Yi‐Wen Meng, Meng‐Ting She, Jia‐Peng Dong, Yingying Zheng, Yao‐Xun Zeng, Wen‐De Zheng, Wei Long, Wing‐Leung Wong   +10 more
wiley   +2 more sources

Treatment of Severe Asthma: Case Report of Fast Action of Mepolizumab in a Patient with Recent SARS-CoV-2 Infection

Life
Asthma is one of the most common chronic inflammatory diseases of childhood with a heterogeneous impact on health and quality of life. Mepolizumab is an antagonist of interleukin-5, indicated as an adjunct therapy for severe refractory eosinophilic ...
Cristiana Indolfi, Giulio Dinardo, Angela Klain, Fabio Decimo, Michele Miraglia del Giudice   +4 more
doaj   +1 more source

IL-4 and IL-5 Secretions Predominate in the Airways of Wistar Rats Exposed to Toluene Diisocyanate Vapor [PDF]

Journal of Preventive Medicine and Public Health, 2014
ObjectivesWe established a Wistar rat model of asthma caused by toluene diisocyanate (TDI) exposure, and investigated the relationship between TDI exposure concentrations and respiratory hypersensitivity, airway inflammation, and cytokine secretions in ...
Kouame Kouadio, Kui-Cheng Zheng, Abdoulaye Abba Toure, Mireille Dosso, Hidemi Todoriki   +4 more
doaj   +1 more source

Case Report: Insulin hypersensitivity in youth with type 1 diabetes

Frontiers in Endocrinology, 2023
ObjectiveImmediate type I, type III, and delayed type IV hypersensitivity reactions to insulin are rare, but potentially serious complications of exogenous insulin administration required for the treatment of type 1 diabetes (T1D).MethodsWe present four ...
Einas H. Alkhatib, Jody B. Grundman, Anna M. Adamusiak, Melena D. Bellin, Melena D. Bellin, Joel P. Brooks, Kevin S. Buckley, Erin M. Janssen, Maleewan Kitcharoensakkul, Kyle P. McNerney, Thea L. Pfeifer, Brooke I. Polk, Brynn E. Marks   +12 more
doaj   +1 more source

Cough hypersensitivity and suppression in COPD

, 2020
Cough reflex hypersensitivity and impaired cough suppression are features of chronic refractory cough (CRC). Little is known about cough suppression and cough reflex hypersensitivity in cough associated with chronic obstructive pulmonary disease (COPD ...
Fletcher, HV, Cho, PSP, Turner, RD, Birring, SS, Jolley, CJ, Patel, IS, Peter S.P. Cho, Irem S. Patel, Richard D. Turner, Hannah V. Fletcher, Surinder S. Birring, Caroline J. Jolley   +11 more
core   +1 more source

Hypersensitivity in the lungs is responsible for acute respiratory failure in COVID‐19 patients: Case series of patients who received high‐dose/short‐term methylprednisolone

Clinical and Translational Allergy, 2021
Background COVID‐19 is a highly contagious respiratory disease caused by the SARS‐CoV‐2 virus. Patients with severe disease have a high fatality rate and face a huge medical burden due to the need for invasive mechanical ventilation.
Meizhu Chen, Changli Tu, Cuiyan Tan, Xiaobin Zheng, Fengfei Sun, Yingjian Liang, Honglei Shi, Jian Wu, Yiying Huang, Zhenguo Wang, Kongqiu Wang, Minmin Lin, Weiming Wu, Hong Zhou, Jing Liu, Jin Huang   +15 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source