Results 11 to 20 of about 1,462,578 (219)
Assessing the Potential to Induce Respiratory Hypersensitivity [PDF]
Toxicological Sciences, 2005 Acute and repeat dose inhalation studies have been an important part of the safety assessment of drugs, chemicals, and other products throughout the world for many years. It is known that damage to the respiratory tract can be triggered either by nonspecific irritation or by specific immune-mediated pathogenesis, and it is acknowledged that traditional
Holsapple, Michael P. +7 more
semanticscholar +4 more sources
Expert opinion on the cough hypersensitivity syndrome in respiratory medicine [PDF]
European Respiratory Journal, 2014 In 2011, a European Respiratory Society Task Force embarked on a process to determine the position and clinical relevance of the cough hypersensitivity syndrome, a disorder characterised by troublesome coughing often triggered by low levels of thermal, mechanical or chemical exposure, in the management of patients with chronic cough.
Morice, Alyn H. +12 more
semanticscholar +5 more sources
Intermittent hypercapnic hypoxia induces respiratory hypersensitivity to fentanyl accompanied by tonic respiratory depression by endogenous opioids. [PDF]
J Physiol, 2020 Sleep apnoea increases susceptibility to opioid‐induced respiratory depression (OIRD). Endogenous opioids are implicated as a contributing factor in sleep apnoea.
Brackley AD, Andrade MA, Toney GM.
europepmc +2 more sources
American Journal of Respiratory and Critical Care Medicine, 2020 Rationale: Aspirin-exacerbated respiratory disease is characterized by severe asthma, nonsteroidal antiinflammatory drug hypersensitivity, nasal polyposis, and leukotriene overproduction.
Yuma Fukutomi +2 more
exaly +2 more sources
The Respiratory Microbiome in Chronic Hypersensitivity Pneumonitis Is Distinct from That of Idiopathic Pulmonary Fibrosis [PDF]
American Journal of Respiratory and Critical Care Medicine, 2020 Rationale: Chronic hypersensitivity pneumonitis (CHP) is a condition that arises after repeated exposure and sensitization to inhaled antigens. The lung microbiome is increasingly implicated in respiratory disease, but, to date, no study has investigated
R. Invernizzi +19 more
semanticscholar +2 more sources
Respiratory hypersensitivity reaction related to ingestion of raspberry
Journal of Cutaneous Immunology and Allergy, 2023 A 27‐year‐old woman developed dyspnea and wheezing within 10 min after eating a piece of raspberry walnut cake, and was successfully treated with intravenous corticosteroid and intramuscular injection of adrenaline.
Yuki Akamatsu +6 more
doaj +2 more sources
Evaluation of a translational swine model of respiratory hypersensitivity induced by exposure to Phleum pratense pollen allergens [PDF]
Frontiers in AllergyIntroductionAsthma is a disease characterized by chronic inflammation of the airway mucosa that causes tissue remodeling and a reversible decrease in airflow.
Jessica Ledesma-Aparicio +7 more
doaj +2 more sources
Cough Hypersensitivity Syndrome: Why Its Use Is Inappropriate in Children
Journal of Clinical Medicine, 2023 In children and adults, chronic cough is a common symptom presenting to health professionals worldwide. It is internationally accepted that children with chronic cough should be managed with pediatric specific management guidelines.
A. Chang +6 more
semanticscholar +2 more sources
American Journal of Respiratory and Critical Care Medicine, 2020 Background: This guideline addresses the diagnosis of hypersensitivity pneumonitis (HP). It represents a collaborative effort among the American Thoracic Society, Japanese Respiratory Society, and Asociación Latinoamericana del Tórax. Methods: Systematic
Ganesh Raghu +2 more
exaly +2 more sources
Carboplatin-Induced Hypersensitivity Reaction
Case Reports in Oncology, 2012 We describe a 65-year-old female with relapsed ovarian cancer who developed a severe hypersensitivity reaction during the second cycle of carboplatin treatment.
Evangelos Potolidis, Charalampos Mandros
doaj +2 more sources