Results 51 to 60 of about 955,664 (289)

Non-steroidal Anti-inflammatory Drug Hypersensitivity in Children: From Urticaria to NSAID-Exacerbated Respiratory Disease

Forbes Tıp Dergisi
Objective: Non-steroidal anti-inflammatory drug (NSAID) hypersensitivity is one of the leading causes of drug hypersensitivity in children. However, data on phenotype distribution according to the 2025 World Allergy Organization (WAO) classification and ...
Özgen SOYÖZ, Figen ÇELEBİ ÇELİK, Selime ÖZEN BÖLÜK, İlke TAŞKIRDI, Mehmet Şirin KAYA, İdil AKAY HACI, Canan Şule KARKINER, Özlem SANCAKLI, Demet CAN   +8 more
doaj   +1 more source

A case of delayed severe hypersensitivity reaction during Genexol-PM® infusion

, 2021
Although Taxol® is one of the most successful drugs in current cancer chemotherapy against solid tumors, a major problem is hypersensitivity reactions that arises as a consequence of activation of the complement (C) system, "C activation ...
이진화, 조영주, 류연주, 천은미, 장중현   +4 more
core   +1 more source

Developmental Environmental Chronotoxicity by Polystyrene Nanoplastics Exacerbates High‐Fat Diet‐Induced Pediatric MAFLD Through Circadian Disruption and Mitochondrial Dysfunction

Advanced Science, EarlyView.
Polystyrene nanoplastics exacerbate high‐fat diet‐induced metabolic dysfunction in an age‐dependent manner. Juvenile mice exhibit greater susceptibility, characterized by circadian disruption, impaired mitochondrial function, reduced energy metabolism, and enhanced hepatic lipid accumulation.
Peihao Xu, Shuting Huang, Leilei Zhu, Junyi Huang, Kewei Li, Guangming Li, Jiannong Wu, Mingyuan Zhou, Fangmei Zhou, Zhishan Ding, Yingzhi Shen   +10 more
wiley   +1 more source

Immunization and Respiratory Diseases Bulletin [PDF]

March 8, 2024, 4:15 PM EDTUpdates on respiratory illness and vaccine-preventable diseases.Formerly called: CDC Respiratory Virus ...

core   +6 more sources

Chemical respiratory sensitization—Current status of mechanistic understanding, knowledge gaps and possible identification methods of sensitizers

Frontiers in Toxicology
Respiratory sensitization is a complex immunological process eventually leading to hypersensitivity following re-exposure to the chemical. A frequent consequence is occupational asthma, which may occur after long latency periods.
Rita Hargitai, Lucia Parráková, Tünde Szatmári, Pablo Monfort-Lanzas, Pablo Monfort-Lanzas, Valentina Galbiati, Karine Audouze, Florence Jornod, Yvonne C. M. Staal, Sabina Burla, Aline Chary, Arno C. Gutleb, Katalin Lumniczky, Rob J. Vandebriel, Johanna M. Gostner   +14 more
doaj   +1 more source

Addressing opioid tolerance and opioid‐induced hypersensitivity: Recent developments and future therapeutic strategies

Pharmacology Research & Perspectives, 2021
Opioids are a commonly prescribed and efficacious medication for the treatment of chronic pain but major side effects such as addiction, respiratory depression, analgesic tolerance, and paradoxical pain hypersensitivity make them inadequate and unsafe ...
Faris Khan, Aman Mehan
doaj   +1 more source

Metabolic‐Redox Remodeling of Inflammatory Synovium by Mannose‐Modified Selenium Nanoparticles for Osteoarthritis Therapy

Advanced Science, EarlyView.
Elevated GLUT1‐driven glycolysis and disrupted selenoprotein‐dependent redox homeostasis drive osteoarthritic progression. Intra‐articular mannose‐modified selenium nanoparticles (M‐SeNPs) selectively target hypermetabolic synovial cells to reprogram aberrant glycolysis and restore endogenous antioxidant defenses.
Yu‐Qing Zou, Chen‐Hao Xu, Bo‐Wei Li, Leung Chan, Yi‐Di Xu, Han‐Bo Su, Rui Peng, Fang‐Ji Luo, Ya‐Chen Peng, Zhen‐Yan Li, Vincent Kam Wai Wong, Xiao‐Fei Zheng, Xing Ma, Zhen‐Gang Zha, Tianfeng Chen, Huan‐Tian Zhang   +15 more
wiley   +1 more source

Concordance Analysis of ALEX‐2, ImmunoCAP, and Prick Test for Respiratory Allergies in Lima, Peru

Immunity, Inflammation and Disease
Background Accurate identification of respiratory allergen sensitization is essential for managing asthma and allergic rhinitis (AR). While Skin Prick Test (SPT) and ImmunoCAP are standard diagnostic tools, exploratory comparative data for the novel ...
César A. Galván, Rafael Durán, José Ignacio Larco, Juan Carlos Gomez de la Torre   +3 more
doaj   +1 more source

Multidisciplinary Discussion for Fibrotic Hypersensitivity Pneumonitis with a Positive Antigen Avoidance

Journal of Asthma and Allergy, 2023
Ryo Okuda,1 Tamiko Takemura,2 Toshihiro Misumi,3 Eri Hagiwara,1 Takashi Ogura1 1Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan; 2Department of Pathology, Kanagawa Cardiovascular and Respiratory Center,
Okuda R, Takemura T, Misumi T, Hagiwara E, Ogura T   +4 more
doaj  

Drug allergy and hypersensitivity: still a hot topic

, 2009
Drug allergy and hypersensitivity: still a hot ...
Romano, Antonino
core   +1 more source