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2022 Alzheimer's disease facts and figures
Alzheimer's & Dementia, 2022This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, use and costs of care, and the overall impact on family caregivers, the dementia workforce and society.
Anonymous
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Impaired Glucose Metabolism in AlzheimerÂ’s Disease and Diabetes
Enzyme Engineering, 2014Several epidemiological studies provide evidence that type 2 diabetes mellitus increases the risk of developing Alzheimer’s disease significantly. Both disorders share certain abnormal biological mechanisms such as impaired glucose metabolism, insulin resistance, increased β-amyloid formation, oxidative stress, and the presence of advanced glycation ...
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A Voxel-Based Morphometry Study in AlzheimerÂ’s Disease and Mild Cognitive Impairment
Journal of Psychiatry, 2015Objectives: A number of structural magnetic resonance imaging (MRI) studies have demonstrated grey matter (GM) atrophy in subjects with mild cognitive impairment (MCI) and Alzheimer’s disease (AD). We used a voxel-based morphometric (VBM) approach to evaluate the patterns of atrophy in GM in subjects with AD and MCI in comparison to control subjects ...
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Differences in BDNF Serum Levels in Patients with AlzheimerÂ’s Disease and Mild Cognitive Impairment
Journal of Psychiatry, 2015Objectives: A great deal of research has been conducted into the possible involvement of neurotrophins such as brain-derived neurotrophic factor (BDNF) in the pathogenesis of Alzheimer’s disease (AD). We hypothesized that lower BDNF serum levels may be associated with cognitive decline.
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Alzheimer's disease: genes, proteins, and therapy.
Physiological Reviews, 2001D. Selkoe
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