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Alzheimer's disease: genes, proteins, and therapy.

Physiological Reviews, 2001
Rapid progress in deciphering the biological mechanism of Alzheimer's disease (AD) has arisen from the application of molecular and cell biology to this complex disorder of the limbic and association cortices.
D. Selkoe
semanticscholar   +1 more source

A new rating scale for Alzheimer's disease.

American Journal of Psychiatry, 1984
A new rating instrument, the Alzheimer's Disease Assessment Scale, was designed specifically to evaluate the severity of cognitive and noncognitive behavioral dysfunctions characteristic of persons with Alzheimer's disease.
W. Rosen, R. Mohs, K. Davis
semanticscholar   +1 more source

Alzheimer's disease: the amyloid cascade hypothesis.

Science, 1992
In both metazoan development and metastatic cancer, migrating cells must carry out a detailed, complex program of sensing cues, binding substrates, and moving their cytoskeletons.
J. Hardy, G. Higgins
semanticscholar   +1 more source

A Voxel-Based Morphometry Study in AlzheimerÂ’s Disease and Mild Cognitive Impairment

Journal of Psychiatry, 2015
Objectives: A number of structural magnetic resonance imaging (MRI) studies have demonstrated grey matter (GM) atrophy in subjects with mild cognitive impairment (MCI) and Alzheimer’s disease (AD). We used a voxel-based morphometric (VBM) approach to evaluate the patterns of atrophy in GM in subjects with AD and MCI in comparison to control subjects ...
Hyun Ok Kim, Yo Sup Kim, Kang Joon Lee
openaire   +2 more sources

Expression of LIF and LIF receptor beta in Alzheimer’s and Parkinson’s diseases

Acta Neurologica Scandinavica, 2010
Signaling through the leukemia inhibitory factor (LIF) receptor (LIFR) is crucial for nervous system development. There are few studies concerning the expression of LIF and LIFR in normal and degenerating adult human brain.To study the expression of LIF and LIFR in Alzheimer's disease (AD), Parkinson's disease (PD), and control brains.LIF and LIFR mRNA
Matias Röyttä   +5 more
openaire   +3 more sources

Onconephrology: The intersections between the kidney and cancer

Ca-A Cancer Journal for Clinicians, 2021
Mitchell H Rosner   +2 more
exaly  

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Nature, 1991
A. Goate   +20 more
semanticscholar   +1 more source

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