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Maturitas, 1999
This article reviews the clinical and neuropathological features of Alzheimer's disease, its known genetic and non-genetic risk factors, procedures used to make the diagnosis and rule out other reversible and non-reversible forms of dementia, and the treatment strategies used to help patients and their families cope with the problem.
E M, Reiman, R J, Caselli
openaire +2 more sources
This article reviews the clinical and neuropathological features of Alzheimer's disease, its known genetic and non-genetic risk factors, procedures used to make the diagnosis and rule out other reversible and non-reversible forms of dementia, and the treatment strategies used to help patients and their families cope with the problem.
E M, Reiman, R J, Caselli
openaire +2 more sources
The Lancet, 2016
Although the prevalence of dementia continues to increase worldwide, incidence in the western world might have decreased as a result of better vascular care and improved brain health. Alzheimer's disease, the most prevalent cause of dementia, is still defined by the combined presence of amyloid and tau, but researchers are gradually moving away from ...
Gholamreza Azizi, Abbas Mirshafiey
openaire +5 more sources
Although the prevalence of dementia continues to increase worldwide, incidence in the western world might have decreased as a result of better vascular care and improved brain health. Alzheimer's disease, the most prevalent cause of dementia, is still defined by the combined presence of amyloid and tau, but researchers are gradually moving away from ...
Gholamreza Azizi, Abbas Mirshafiey
openaire +5 more sources
Continuum, 2022
Alzheimer disease (AD) is the most common cause of dementia in adults (mid to late life), highlighting the importance of understanding the risk factors, clinical manifestations, and recent developments in diagnostic testing and therapeutics.Advances in fluid (CSF and blood-based) and imaging biomarkers are allowing for a more precise and earlier ...
openaire +2 more sources
Alzheimer disease (AD) is the most common cause of dementia in adults (mid to late life), highlighting the importance of understanding the risk factors, clinical manifestations, and recent developments in diagnostic testing and therapeutics.Advances in fluid (CSF and blood-based) and imaging biomarkers are allowing for a more precise and earlier ...
openaire +2 more sources
Seminars in Neurology, 2013
Alzheimer's disease (AD) is the most common neurodegenerative cause of dementia and is responsible for significant individual morbidity and mortality, and economic impact on the health care system. Neurodegeneration (including neuronal atrophy and/or loss) are attributed to extraneuronal toxic amyloid oligomers and proteins, intraneuronal ...
Carly, Oboudiyat +4 more
openaire +2 more sources
Alzheimer's disease (AD) is the most common neurodegenerative cause of dementia and is responsible for significant individual morbidity and mortality, and economic impact on the health care system. Neurodegeneration (including neuronal atrophy and/or loss) are attributed to extraneuronal toxic amyloid oligomers and proteins, intraneuronal ...
Carly, Oboudiyat +4 more
openaire +2 more sources
Lecanemab in Early Alzheimer’s Disease
New England Journal of Medicine, 2023Randall J Bateman +2 more
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Leveraging preclinical models for the development of Alzheimer disease therapeutics
Nature Reviews Drug Discovery, 2020Kimberly A Scearce-Levie +2 more
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