Results 71 to 80 of about 5,910,398 (387)
Clinical Infectious Diseases, 2015 These guidelines are intended for use by infectious disease specialists, orthopedic surgeons, neurosurgeons, radiologists, and other healthcare professionals who care for patients with native vertebral osteomyelitis (NVO).
E. Berbari +11 more
semanticscholar +1 more source
A novel IgE antibody targeting the prostate-specific antigen as a potential prostate cancer therapy [PDF]
, 2013 Prostate cancer (PCa) is the second leading cause of cancer deaths in men in the United States. The prostate-specific antigen (PSA), often found at high levels in the serum of PCa patients, has been used as a marker for PCa detection and as a target of ...
A Katzenwadel +76 more
core +3 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Panorama Económico, 2019 Este trabajo analiza el ordenamiento político administrativo del territorio en los lugares donde habían surgido sitios de libres de todos los colores. También revisa el papel desempeñado por la vecindad para su integración al orden hispánico. Finalmente,
Jorge Conde Calderon +1 more
doaj +1 more source
Clinical Infectious Diseases, 2016 Evidence-based guidelines for implementation and measurement of antibiotic stewardship interventions in inpatient populations including long-term care were prepared by a multidisciplinary expert panel of the Infectious Diseases Society of America and the
T. Barlam +21 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
A latinidade do conceito de América Latina
Revista Geographia, 2013 De uma maneira geral, assumimos de modo tão naturalizado as designações e os recortes geográficos das regiões que visualizamos em mapas ou que utilizamos como referência de pertencimento e localização, que dificilmente nos questionamos sobre os processos
Pedro de Araújo Quental
doaj +1 more source
Repensando las desigualdades sociales en América Latina [PDF]
, 2014 Fil: Kessler, Gabriel. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación. Instituto de Investigaciones en Humanidades y Ciencias Sociales (UNLP-CONICET); Argentina.
Kessler, Gabriel, Tizziani, Ania
openaire
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Cadernos de História da EducaçãoEsta resenha objetiva tecer uma análise a respeito da obra “A educação nas independências da América: a circulação do plano de ensino mútuo (1810–1830)” (OLIVATO, 2023), da historiadora Laís Olivato, fruto de pesquisa de doutorado desenvolvida no ...
Tânia Gomes Mendonça
doaj +1 more source