Results 51 to 60 of about 3,022,233 (266)

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Una nota biográfica sobre Jerónimo de Cáncer y Velasco

open access: yesRevista de Literatura, 2015
La fecha y lugar de nacimiento del dramaturgo Jerónimo de Cáncer han sido cuestionados en numerosas ocasiones. Distintos investigadores intentaron localizar —de manera infructuosa— la documentación sobre el origen del poeta, lo que ha impedido fijar una ...
Elena Martínez Carro   +1 more
doaj   +1 more source

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek   +13 more
wiley   +1 more source

WETWALL - an innovative design concept for the treatment of wastewater at an urban scale [PDF]

open access: yes, 2018
Rising temperatures, increasing food demand and scarcity of water and land resources highlight the importance of promoting the sustainable expansion of agriculture to our urban environment, while preserving water resources.
Arias, Carlos Alberto   +7 more
core   +4 more sources

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich   +5 more
wiley   +1 more source

“A educação nas independências da América”. Uma análise sobre a busca da formação de cidadãos para um novo momento histórico

open access: yesCadernos de História da Educação
Esta resenha objetiva tecer uma análise a respeito da obra “A educação nas independências da América: a circulação do plano de ensino mútuo (1810–1830)” (OLIVATO, 2023), da historiadora Laís Olivato, fruto de pesquisa de doutorado desenvolvida no ...
Tânia Gomes Mendonça
doaj   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Inicios de la misión en América: Isabel La Católica, Colón y Boil

open access: yesHispania Sacra, 2001
Análisis del inicio del cristianismo en América, refiriendo la construcción de los primeros templos en los años del descubrimiento y las primeras exploraciones del Nuevo Mundo.
Juan B. Olaechea Labayen
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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