Results 51 to 60 of about 5,451,349 (285)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Africa in America, for the English teaching at the University

Revista MENDIVE, 2022
The African culture is an intrinsic part of the culture in America, understood as a continent, and not only as the United States of America. It is expressed in language, art, music, dance, literature, history, etc. The exclusion of the African culture in
Rodolfo Acosta Padrón, Ileana Isabel Herrera Arencibia, Antonio García García   +2 more
doaj  

Humanismo clasicista mediterráneo y concepción antropológica del mundo: el caso de los jesuitas

Hispania, 1996
Se propone por el autor una reconsideración del papel de los jesuitas en la historia científica de la España Moderna, con énfasis principal en su contribución lingüística y etnográfica.
Fermín del Pino
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Científicos americanos en las cortes constituyentes. La cuestión ultramarina

Revista de Indias, 2003
Con este estudio pretendemos contribuir al mayor conocimiento sobre un capítulo poco estudiado de la historia de la ciencia hispanoamericana. Lo haremos a través del seguimiento de las actuaciones como diputados en las Cortes españolas de tres destacados
Jose Luis Maldonado Polo
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

«Como antiguas estatuas de bronce» Sobre la disolución del clasicismo en la relación histórica de un viaje a las regiones equinocciales del nuevo mundo, de Alejandro de Humboldt

Revista de Indias, 2001
La interpretación de América usando motivos clasicistas como modelos imperiales de apropiación, «antiquización», es una de las principales estrategias retóricas en los relatos de viajes de Alejandro de Humboldt.
Oliver Lubrich
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Pandemia-sindemia de la Covid-19 en América al 30/08/2023

Tecnología en Marcha
El presente estudio describe la evolución de la pandemia-sindemia de la Covid-19 en América al 30/08/2023, el cual cubre desde la declaración de la pandemia por parte de la OMS el 11/03/2020, la declaración del fin de la emergencia sanitaria al 06/05 ...
Darner Mora Alvarado
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source