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CONSTRUIR LA HISTORIA DE LA ARQUITECTURA ENTRE DOS CONTINENTES. LA APORTACIÓN DE PEDRO JOSÉ MÁRQUEZ EN LOS APUNTAMIENTOS POR ORDEN ALFABÉTICO

open access: yesLaboratorio de Arte
La relevancia de Pedro José Márquez y sus trabajos es conocida. Sin embargo, su aportación historiográfica es susceptible de ulteriores análisis, especialmente la contenida en los Apuntamientos por orden alfabético.
Miriam Cera-Brea
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The prolonged Brazilian shadow of Santa Teresa de Jesús

open access: yesRevista de Estudios Brasileños, 2016
Sáez Martínez, B. (Ed.). (2015). Santa Teresa de Ávila en Brasil. Madrid: Centro de Publicaciones. Ministerio de Educación, Cultura y Deporte. The book being reviewed was originally written to fill a gap in the bibliography concerning Saint Teresa de ...
Antonio MAURA
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

El choque del descubrimiento

open access: yesCiencia y Sociedad, 1992
Este texto de Frank Moya Pons reflexiona los grandes rasgos de cómo comenzó aquello que los españoles del siglo XVI se ufanan de llamar "la conquista".
Frank Moya Pons
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

La integración política de negros, mulatos, pardos y zambos al orden hispánico: los sitios de libres en el Nuevo Reino de Granada

open access: yesPanorama Económico, 2019
Este trabajo analiza el ordenamiento político administrativo del territorio en los lugares donde habían surgido sitios de libres de todos los colores. También revisa el papel desempeñado por la vecindad para su integración al orden hispánico. Finalmente,
Jorge Conde Calderon   +1 more
doaj   +1 more source

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