Results 41 to 50 of about 1,291,457 (215)

Una nota biográfica sobre Jerónimo de Cáncer y Velasco

Revista de Literatura, 2015
La fecha y lugar de nacimiento del dramaturgo Jerónimo de Cáncer han sido cuestionados en numerosas ocasiones. Distintos investigadores intentaron localizar —de manera infructuosa— la documentación sobre el origen del poeta, lo que ha impedido fijar una ...
Elena Martínez Carro, Alejandro Rubio San Román   +1 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

“A educação nas independências da América”. Uma análise sobre a busca da formação de cidadãos para um novo momento histórico

Cadernos de História da Educação
Esta resenha objetiva tecer uma análise a respeito da obra “A educação nas independências da América: a circulação do plano de ensino mútuo (1810–1830)” (OLIVATO, 2023), da historiadora Laís Olivato, fruto de pesquisa de doutorado desenvolvida no ...
Tânia Gomes Mendonça
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

CONSTRUIR LA HISTORIA DE LA ARQUITECTURA ENTRE DOS CONTINENTES. LA APORTACIÓN DE PEDRO JOSÉ MÁRQUEZ EN LOS APUNTAMIENTOS POR ORDEN ALFABÉTICO

Laboratorio de Arte
La relevancia de Pedro José Márquez y sus trabajos es conocida. Sin embargo, su aportación historiográfica es susceptible de ulteriores análisis, especialmente la contenida en los Apuntamientos por orden alfabético.
Miriam Cera-Brea
doaj   +1 more source

Inicios de la misión en América: Isabel La Católica, Colón y Boil

Hispania Sacra, 2001
Análisis del inicio del cristianismo en América, refiriendo la construcción de los primeros templos en los años del descubrimiento y las primeras exploraciones del Nuevo Mundo.
Juan B. Olaechea Labayen
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Africa in America, for the English teaching at the University

Revista MENDIVE, 2022
The African culture is an intrinsic part of the culture in America, understood as a continent, and not only as the United States of America. It is expressed in language, art, music, dance, literature, history, etc. The exclusion of the African culture in
Rodolfo Acosta Padrón, Ileana Isabel Herrera Arencibia, Antonio García García   +2 more
doaj  

Humanismo clasicista mediterráneo y concepción antropológica del mundo: el caso de los jesuitas

Hispania, 1996
Se propone por el autor una reconsideración del papel de los jesuitas en la historia científica de la España Moderna, con énfasis principal en su contribución lingüística y etnográfica.
Fermín del Pino
doaj   +1 more source