Results 71 to 80 of about 1,291,457 (215)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Europa y América en la revolución geodemográfica

Estudios Demográficos y Urbanos, 2005
El trabajo establece un parangón entre Europa y América tanto de sus vivencias demográficas en el pasado con el Nuevo Mundo, como de las repercusiones futuras de las demografías de ambas regiones en un mundo globalizado. Con diversos indicadores el autor
Massimo Livi Bacci
doaj  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Tocqueville's "Sacred Ark"

Araucaria, 2019
Este artículo explora diversos aspectos constitutivos de la “nueva ciencia de la política” de Tocqueville. Centrado en sus componentes interdisciplinarios, comparativos, normativos y políticos, trata de poner de manifiesto la sofisticación conceptual y ...
Aurelian Craiutu
doaj   +1 more source

Efecto del Patrocinio de la Copa América en las percepciones de Luis Vuitton: una perspectiva internacional

Revista Galega de Economía, 2014
Sobre la base de una amplia revisión de la literatura dedicada a los estudios experimentales sobre los efectos del patrocinio en las percepciones de la marca, en el presente estudio se desarrolla conceptualmente el proceso de persuasión en la actividad de patrocinio.
openaire   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

El Siglo de Oro desde una consideración atlántica: Miguel de Cervantes y el Inca Garcilaso

Cuadernos del CILHA
En la actualidad se desarrolla cierto enfoque de la literatura hispánica del Siglo de Oro que pone el acento en las relaciones de coevidad e intercambio entre España y América.
Graciela Maturo
doaj  

Lições da América: o problema do americanismo em Tocqueville Lessons from America: the problem of americanism in Tocqueville

Lua Nova: Revista de Cultura e Política, 1993
Quem deve prestar lições a quem: a América à Europa ou vice-versa? O autor interpreta o pensamento de Tocqueville à luz dessa questão, trabalhando com o conceito de americanismo - isto é, a conciliação que se tornou possível nos Estados Unidos, sem que rupturas revolucionárias ocorressem, entre estado social de igualdade e liberdade, entre ...
openaire   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source