Results 111 to 120 of about 14,795,913 (293)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Radical, reformist and aborted liberalism: origins of national regimes in Central America
América Latina Hoy, 2011 During the twentieth century, the countries of Central America were characterized by remarkably different political regimes: military-authoritarianism in Guatemala and El Salvador, progressive democracy in Costa Rica and traditional-authoritarianism in ...
James MAHONEY
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
La interacción transnacional de la sociedad civil centroamericana frente a la violencia juvenil
América Latina Hoy, 2009 RESUMEN: La violencia juvenil es uno de los problemas sociales más importantes en Guatemala, Honduras y El Salvador. La expansión de las pandillas juveniles ha sido enfrentada por los gobiernos de estas naciones por medio de la adopción de medidas ...
Alberto MARTÍN ÁLVAREZ +1 more
doaj +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
NORMAS DE PUBLICACIÓN REVISTA GEOGRÁFICA DE AMÉRICA CENTRAL
, 2011 NORMAS DE PUBLICACIÓN REVISTA GEOGRÁFICA DE AMÉRICA ...
Geográfica de América Central, Revista
core
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Vicente Sáenz: el antifascismo itinerante o los fantasmas del patriarca
Cuadernos Inter.c.a.mbio sobre Centroamérica y el Caribe, 2012 El artículo explica el papel y la vivencia del intelectual costarricense Vicente Sáenz en la era antifascista, planteando para ello dos hipótesis: que el caso de Sáenz resulta un contrapunto para hacer lectura de la evolución y desenlace del ...
Dennis Arias Mora
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