Results 121 to 130 of about 14,795,913 (293)
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Revista Cubana de Higiene y EpidemiologíaSe realizó un estudio descriptivo retrospectivo en el área metropolitana de la Región Sanitaria No. 3 de Honduras, con el propósito de identificar características sociodemográficas, clínicas y epidemiológicas de la leishmaniosis.
Grisel E. Risco Oliva +2 more
doaj
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
Influencia de la personalidad en el liderazgo
Ciencia UNEMI, 2018 El presente análisis busca comprender las características de un líder con el objetivo de entender a quienes manejan las empresas y organizaciones. En este análisis se analizan ideas y conceptos desde Aristóteles con su definición de los 5 factores de la ...
Santiago Nájera Acuña +2 more
doaj
Central's first homecoming; male students standing on street in single file line
, 1920 In Central Methodist University (formerly Central College)'s first homecoming parade, male students in costume stand in single file on an unpaved road in Fayette ...
Central Methodist University, Smiley Memorial Library
core +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
Exploring social innovation in health in Central America and the Caribbean. [PDF]
Rev Panam Salud Publica, 2020 Mothe J +4 more
europepmc +1 more source
A pregnant woman with COVID-19 in Central America
Travel Medicine and Infectious Disease, 2020 Lysien I. Zambrano +11 more
semanticscholar +1 more source