Results 81 to 90 of about 7,577,728 (211)
Radical, reformist and aborted liberalism: origins of national regimes in Central America
América Latina Hoy, 2011 During the twentieth century, the countries of Central America were characterized by remarkably different political regimes: military-authoritarianism in Guatemala and El Salvador, progressive democracy in Costa Rica and traditional-authoritarianism in ...
James MAHONEY
doaj +1 more source
FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
La interacción transnacional de la sociedad civil centroamericana frente a la violencia juvenil
América Latina Hoy, 2009 RESUMEN: La violencia juvenil es uno de los problemas sociales más importantes en Guatemala, Honduras y El Salvador. La expansión de las pandillas juveniles ha sido enfrentada por los gobiernos de estas naciones por medio de la adopción de medidas ...
Alberto MARTÍN ÁLVAREZ +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Boletín Observatorio América Latina-Asia Pacífico
, 2015 Observatorio América Latina - Asia Pacífico.Evolución del comercio exterior -- Protocolo comercial de la Alianza del Pacífico: avances y desafíos para América Latina y el ...
core +1 more source
Cambio estructural: crecimiento y (des) industrialización en América Latina (1950-2005)
, 2013 A partir del marco teórico del crecimiento basado en el cambio estructural, el doctor Moncayo examina la relación entre industrialización y crecimiento en América Latina y en Colombia.
Moncayo Jiménez, Édgar; Universidad Central
core
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source