Results 31 to 40 of about 16,928 (219)
REGULAÇÕES INSTITUCIONAIS E INTEGRAÇÃO CULTURAL: UM BINÔMIO VIÁVEL
O artigo a seguir explora e enfatiza alguns aspectos da pesquisa de doutorado da autora. Apresenta as formas e princípios organizativos de grupos de Alcoólicos Anônimos no Brasil e no Uruguai, e analisa relações entre suas regulações institucionais e o ...
Eliane Ganev
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Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
El artículo identifica algunos de los principales rasgos que caracterizan la reactivación de la economía y, en especial, de la industria argentina en la posconvertibilidad, a partir del quiebre del régimen de conversión fija con el dólar estadounidense ...
Daniel Aspiazu, Martín Schorr
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
This study aimed to analyze the occurrence of seasonal variations in the number of captures of Artibeus lituratus and Sturnira lilium in the upper strata of an Atlantic Forest remnant in southern Brazil. It was conducted in the town of Pedras Grandes, in
Fernando Carvalho +2 more
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A VERSÃO BRASILEIRA DOS DIREITOS HUMANOS. UMA REFLEXÃO POLÍTICA-ANTROPOLÓGICA DOS PNDHS I E II
Este ensaio trata do Plano Nacional de Direitos Humanos – PNDH (I e II), criado no Brasil em sua primeira versão em 1996 e complementado em 1999, durante o governo de Fernando Henrique Cardoso.
Neusa Romero Barazal
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Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
BUENOS AIRES DANS LES ANNÉS 90: GOUVERNANCE URBAINE DANS UNE MÉTROPOLE DIVISÉE
Que signifie parler de gouvernance urbaine, dans une grande métropole de 12 millions d’habitants qui a vu, dans les années 90, se creuser la coupure entre la ville-centre dopée par la nouvelle économie et les immenses périphéries dévastées par la ...
Marie-France Prévôt Schapira
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