Results 71 to 80 of about 173,577 (262)

Congruence amalgamation of lattices

open access: yes, 2005
J. Tuma proved an interesting "congruence amalgamation" result. We are generalizing and providing an alternate proof for it. We then provide applications of this result: --A.P.
Grätzer, George   +2 more
core  

The Metric Dimension of Amalgamation of Cycles [PDF]

open access: yes, 2010
For an ordered set W = {w_1, w_2 , ..., w_k } of vertices and a vertex v in a connected graph G, the representation of v with respect to W is the ordered k-tuple r(v|W) = (d(v,w_1), d(v,w_2 ), ..., d (v,w_k )), where d(x,y) represents the distance ...
Baskoro, Edy Tri   +3 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Turbulence, amalgamation and generic automorphisms of homogeneous structures [PDF]

open access: yes, 2006
We study topological properties of conjugacy classes in Polish groups, with emphasis on automorphism groups of homogeneous countable structures. We first consider the existence of dense conjugacy classes (the topological Rokhlin property).
Kechris, Alexander S.   +1 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

THE IMPACT OF GLOBALIZATION ON THE DEVELOPMENT OF STOCK MARKETS

open access: yesВестник Кемеровского государственного университета, 2013
The paper addresses the process of globalization and the causing it. The impaact of globalization on the internationally stock market is considered. A comprehensive analysisof trading platforms mergers and take-overs at the regional and global levels was
V. I. Buvaltseva, V. V. Chechin
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

From paperwork to pixels: workload and digital governance in Armenian local authorities

open access: yesFrontiers in Political Science
This study examines the impact of amalgamation reforms on workload and digital governance within Armenian local authorities, against a backdrop of decentralization and government consolidation.
Arman Gasparyan
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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