Results 41 to 50 of about 78,289 (273)

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

SarA based Novel Therapeutic Candidate against Staphylococcus aureus associated with Vascular Graft Infections

Frontiers in Microbiology, 2015
Despite advances and amalgamation of various fields to develop novel antimicrobial agents, multi-drug resistant (MDR) Staphylococcus aureus remains one of the most significant pathogen. Staphylococcal accessory regulator A (SarA) belongs to the family of
Rekha eArya, Ravikumar eR, Santhosh eRS, S. Adline ePrincy   +3 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Evaluating bionanoparticle infused fungal metabolites as a novel antimicrobial agent

Journal of Advanced Pharmaceutical Technology & Research, 2016
Therapeutic properties of fungal metabolites and silver nanoparticles have been well documented. While fungal metabolites have been used for centuries as medicinal drugs, potential of biogenic silver nanoparticles has recently received attention. We have
Kartikeya Rajpal, Nafe Aziz, Ram Prasad, Ramendra G Varma, Ajit Varma   +4 more
doaj   +1 more source

Non-Absoluteness of Model Existence at $\aleph_\omega$

, 2017
In [FHK13], the authors considered the question whether model-existence of $L_{\omega_1,\omega}$-sentences is absolute for transitive models of ZFC, in the sense that if $V \subseteq W$ are transitive models of ZFC with the same ordinals, $\varphi\in V ...
Milovich, David, Souldatos, Ioannis
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Coherence in amalgamated algebra along an ideal [PDF]

, 2013
Let $f: A\rightarrow B$ be a ring homomorphism and let $J$ be an ideal of $B$. In this paper, we investigate the transfert of the property of coherence to the amalgamation $A\bowtie^{f}J$. We provide necessary and sufficient conditions for $A\bowtie^{f}J$
Communicated Rahim Zaare-nah, Ismaili, K. Alaoui, K. Alaoui Ismaili, N. Mahdou, N. Mahdou   +5 more
core   +1 more source

Amalgamations of classes of Banach spaces with a monotone basis

, 2015
It was proved by Argyros and Dodos that, for many classes $ C $ of separable Banach spaces which share some property $ P $, there exists an isomorphically universal space that satisfies $ P $ as well.
Kurka, Ondřej
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source