Results 51 to 60 of about 78,289 (273)
A DR4, DR5 Targeting Conjugated TRAIL Treatment for Colorectal Carcinogenesis: A Way to Future? [PDF]
Pharmaceutical SciencesTRAIL or tumor necrosis factor-related apoptosis-inducing ligand has been one of the major frontiers for the chemotherapeutic approach to treating carcinogenesis.
Parikshit Roychowdhury +7 more
doaj +1 more source
An amalgamation property for metric groups
Algebra and Discrete Mathematics, 2022 In this paper we show that under some mild assumptions two copies of a metric group can be freely amalgamated over any central subgroup so that the distance between them is sufficiently small.
Popowicz, J., Ivanov, A.
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The Impact of Hajj on the Society of Bangladesh
Ijtimā'iyya, 2018 Millions of Muslims from around the world including Bangladesh pour perform Hajj every year. Being the largest gathering of the Muslims, the Hajj has got immense socio-economic and cultural impacts on every Muslim society as well as Bangladesh.
Md Thowhidul Islam
doaj +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Intersecting Identities in 18th Century Jerusalem: Conversion to Islam
ReligionsThis paper examines conversion to Islam in eighteenth-century Ottoman Jerusalem as a multifaceted transformation negotiated across social, legal, and economic domains. Drawing on Jerusalem Court Registers and the scholar al-Khalīlī’s (d. 1734, Jerusalem)
Alaattin Dolu
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The amalgamation property in normal open induction. [PDF]
Notre Dame Journal of Formal Logic, 1992 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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(Generalized) filter properties of the amalgamated algebra
Archivum Mathematicum, 2022 Let $R$ and $S$ be commutative rings with unity, $f:R\to S$ a ring homomorphism and $J$ an ideal of $S$. Then the subring $R\bowtie^fJ:=\{(a,f(a)+j)\mid a\in R$ and $j\in J\}$ of $R\times S$ is called the amalgamation of $R$ with $S$ along $J$ with respect to $f$. In this paper, we determine when $R\bowtie^fJ$ is a (generalized) filter ring.
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