Results 91 to 100 of about 26,228 (200)

Structural Basis for Asymmetric Conductance of the Influenza M2 Proton Channel Investigated by Solid-State NMR Spectroscopy [PDF]

open access: yes, 2017
The influenza M2 protein forms an acid-activated proton channel that is essential for virus replication. The transmembrane H37 selects for protons under low external pH while W41 ensures proton conduction only from the N terminus to the C terminus and ...
Hong, Mei   +3 more
core   +1 more source

Structure of AI Responses With Complex Patient Analysis for Patient Alternatives and Patient Modifiers

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Background Artificial intelligence (AI) is already a powerful tool that is rapidly growing within the dental sector. Reports of structure and characteristics of AI responses to patient scenarios are limited. Purpose To analyse characteristics and structure of AI responses to prompts for treatment planning alternatives and patient alternatives ...
David C Johnsen   +4 more
wiley   +1 more source

Effect of Repeated Intravenous Amantadine Infusions in Patients with Parkinson's Disease: An Open‐Label Pilot Study

open access: yesClinical and Translational Science, 2019
Amantadine is an antiviral drug available in oral and intravenous forms. Oral amantadine is used to treat the motor symptoms of early Parkinson's disease (PD) and to ameliorate dyskinesia in late‐stage disease.
Alexander Khlebtovsky   +3 more
doaj   +1 more source

The use of a battery of tracking tests in the quantitative evaluation of neurological function [PDF]

open access: yes
A tracking test battery has been applied in a drug trail designed to compare the efficacy of L-DOPA and amantadine to that of L-DOPA and placebo in the treatment of 28 patients with Parkinson's disease.
Albers, J. W.   +3 more
core   +1 more source

Overview, Prevention, and Treatment of Rabies [PDF]

open access: yes, 2009
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90104/1/phco.29.10.1182 ...
Nigg, Andrea Julia, Walker, Pamela L.
core   +1 more source

Parkinson's Disease and Salivary Issues: A Survey

open access: yesGerodontology, EarlyView.
ABSTRACT Background Salivary dysfunction, including xerostomia and drooling, is common in Parkinson's disease and further impairs oral health and quality of life, which are already compromised in this population. Their effective management demands deeper insight into the complexity of salivary dysfunction.
Beau D. M. van Dijk   +3 more
wiley   +1 more source

A Pilot Study of Value of Information Analysis to Support Research Recommendations for the National Institute for Health and Clinical Excellence [PDF]

open access: yes
Background - This project developed as a result of the activities of the Research Teams at the Centre for Health Economics, University of York, and ScHARR at the University of Sheffield in the methods and application of decision analysis and value of ...
Alan Wailoo   +7 more
core  

The possibility of administration of glutamate receptors antagonists in the treatment of parkinson's disease [PDF]

open access: yes, 2016
Parkinson's disease is the slow-progressing chronic neurodegenerative disease. Modern medicine has not yet found methods of curing disease, however, the existing methods of conservative and surgical treatment significantly improve the patient’s quality ...
Avdeeva, N. V.   +3 more
core   +2 more sources

H1N1 Influenza Virus [PDF]

open access: yes, 2015
On April 17, 2009, two patients in the United States were found with Swine-Origin Influenza A (H1N1) virus. This virus was spread to Mexico, Canada, and many other countries.
Consford, Kail, Patel, Drew
core   +1 more source

Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection

open access: yesAdvanced Genetics, Volume 7, Issue 1, March 2026.
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man   +7 more
wiley   +1 more source

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