Results 71 to 80 of about 18,186 (211)

Neurodegenerative Diseases: Epidemiology, Risk Factors, Classification, Pathophysiology, Clinical Features, Diagnosis, and Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He   +4 more
wiley   +1 more source

Amantadine extended-release capsules for levodopa-induced dyskinesia in patients with Parkinson's disease

open access: yes, 2018
Vibhash D Sharma, Kelly E Lyons, Rajesh Pahwa Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA Abstract: Levodopa-induced dyskinesia (LID) is a common motor complication in patients with Parkinson’s disease on ...
Pahwa R, Lyons KE, Sharma VD
core  

Mitochondria in Viral Infections: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Viral infections remodel mitochondrial function through direct viral regulation and infection‐induced changes in host cellular processes. These alterations affect OXPHOS, mitochondrial metabolism, calcium homeostasis, membrane potential, redox regulation, dynamics, and apoptosis, with distinct effects on viral replication and host antiviral responses ...
Ha Young Oh, Hye Jin Shin
wiley   +1 more source

Machine Learning and Structural Analysis for Generation‐Wise Selection of Perylene Diimide Dendrimers Based on Topological Compatibility With Drug Molecules

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
Machine learning and graph‐theoretic descriptors are integrated to evaluate topology‐based compatibility between perylene diimide‐core dendrimer generations and antiviral, antioxidant, and imaging agents. Standardized structural similarity reveals generation‐dependent compatibility patterns, while Gaussian process regression uncovers key structure ...
Zainab Bibi   +5 more
wiley   +1 more source

Fine‐needle aspirates and computed tomography assisting in the diagnosis of cholesteatoma in a dog with recurrent otitis

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary A 10‐year‐old, male, neutered Bichon‐Frisé, with a history of recurrent otitis externa, was presented to a referral centre with sudden‐onset head tilt. Neurological examination was consistent with right peripheral vestibular syndrome and facial neuropathy.
Myrto Spyropoulou   +5 more
wiley   +1 more source

Corticosteroid‐augmented interfascial injections for cancer pain management in a dog

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 9‐year‐old Rottweiler with metastatic osteosarcoma developed severe episodic pain following forelimb amputation and progression of neoplastic disease. Despite extensive multimodal systemic analgesia, including NSAIDs, gabapentin, amantadine and later amitriptyline, the dog showed persistent vocalisation and touch‐evoked pain in the axillary ...
Zita Julianna Szabo   +3 more
wiley   +1 more source

Amantadine-resistant influenza A virus in Taiwan

open access: yes, 2008
[[abstract]]Background and purpose: Amantadine and rimantadine have been used for treatment and prophylaxis of influenza A virus infection. We examined the amantadine susceptibility of field isolates of influenza A virus in Taiwan from 1996 to 1998 to ...
Shih, SR; Lee, CN; Tsai, HR; Chen, GW; Tsao, KC
core  

Amantadine for COVID‐19 [PDF]

open access: yesThe Journal of Clinical Pharmacology, 2020
Grieb, Paweł   +3 more
openaire   +3 more sources

Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta‐analysis

open access: yesAddiction, Volume 121, Issue 11, Page 2897-2958, November 2026.
Abstract Background and aims Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment.
Craig Paterson   +13 more
wiley   +1 more source

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