Objective Some patients have been found to develop intraoperative amaurosis under sub-Tenon’s anesthesia. We explored whether these patients have poor surgical outcomes during mid- to long-term postoperative follow-up.
Qi Zhang +7 more
doaj +1 more source
Progression of phenotype in Leber's congenital amaurosis with a mutation at the LCA5 locus [PDF]
BACKGROUND: Leber’s congenital amaurosis (LCA) accounts for 5% of inherited retinal disease and is usually inherited as an autosomal recessive trait. Genetic and clinical heterogeneity exist.
Inglehearn, C.F. +5 more
core +1 more source
Pupillometric analysis for assessment of gene therapy in Leber Congenital Amaurosis patients [PDF]
Background: Objective techniques to assess the amelioration of vision in patients with impaired visual function are needed to standardize efficacy assessment in gene therapy trials for ocular diseases.
Bennett, Jean, M.D. +5 more
core +3 more sources
Clinical characterization of 66 patients with congenital retinal disease due to the deep-intronic c.2991+1655A>G mutation in CEP290 [PDF]
Purpose: To describe the phenotypic spectrum of retinal disease caused by the c.2991+1655A>G mutation in CEP290 and to compare disease severity between homozygous and compound heterozygous patients.
Bertelsen, Mette +16 more
core +3 more sources
Intracameral lidocaine as supplement to classic topical anesthesia for relieving ocular pain in cataract surgery [PDF]
● AIM: To evaluate safety, efficacy, and patient adherence of intracameral lidocaine as supplement of classic topical anesthetic drops in cataract surgery.
Librando, Aloisa +4 more
core +2 more sources
Rpgrip1 is required for rod outer segment development and ciliary protein trafficking in zebrafish [PDF]
The authors would like to thank the Royal Society of London, the National Eye Research Centre, the Visual Research Trust, Fight for Sight, the W.H. Ross Foundation, the Rosetrees Trust, and the Glasgow Children’s Hospital Charity for supporting this work.
A Eblimit +54 more
core +4 more sources
Vasospastic amaurosis fugax [PDF]
A 54 year old man was admitted because of repeating (10–12/day) visual disturbances in the left eye. He reported shrinkage of the visual fields and a shadow-like visual impairment progressing to complete darkness within about 3 min and lasting about 10 min, followed by complete recovery.
Josef G, Heckmann +4 more
openaire +2 more sources
Urothelial Carcinoma of the Bladder Following BK Virus Infection in a Pediatric Kidney Transplant Recipient. [PDF]
ABSTRACT Background Urothelial bladder carcinoma is extremely rare in children and its association with BK virus infection remains unclear. Methods We describe the case of an 11‐year‐old girl who developed a urothelial carcinoma of the bladder four years after receiving her first kidney transplant.
Ichas M +7 more
europepmc +2 more sources
Blindness incidence in Germany - A population-based study from Württemberg-Hohenzollern [PDF]
Few data on the incidence of blindness in Germany are available. We analysed causes of legal blindness for the region Württemberg-Hohenzollern (population 5.5 million) in order to help fill in this gap.
Klauss, V. +4 more
core +1 more source
Amaurosis in toxaemia of pregnancy
Mathew M, Rajani C, Gulati N
doaj +2 more sources

