Results 61 to 70 of about 374,995 (289)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Layer-by-layer assembly yields thin graphene films with near theoretical conductivity
npj 2D Materials and ApplicationsThin films fabricated from solution-processed graphene nanosheets are of considerable technological interest for a wide variety of applications, such as transparent conductors, supercapacitors, and memristors.
Oran Cassidy +7 more
doaj +1 more source
B[e] stars at the highest angular resolution: the case of HD87643 [PDF]
, 2009 New results on the B[e] star HD87643 are presented here. They were obtained with a wide range of different instruments, from wide-field imaging with the WFI camera, high resolution spectroscopy with the FEROS instrument, high angular resolution imaging ...
Chesneau, Olivier +3 more
core +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Self-Organized Criticality in Protein Folding Simulations with AMBER Parameters [PDF]
, 2014 AMBER (Assisted Model Building with Energy Refinement) is a force field that allows for the simulation of proteins. Basic proteins were folded by a Monte-Carlo algorithm parameterized by AMBER on MATLAB. Simulations exhibited self-organized critical (SOC)
Sim, Yura
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
BIOLOGICAL ACTIVITY OF SUCCINIC ACIDS [PDF]
Biotechnologia Acta, 2018 The aim of the research was to detect the biological activity of aqueous solutions of various samples of amber from the Trancedniestria province, and to characterize their effect on the physiological processes of higher plants.
N. Ya. Levchyck +5 more
doaj +1 more source
More records of mosses from Dominican amber [PDF]
, 2006 Hypnum spec., Orthostichella cf. pentasticha, Syrrhopodon flexifolius and Porotrichum aff. substriatum are recorded from Dominican amber (c. 25 mio yrs. b.p.).
Frahm, Jan-Peter
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Modeling the process of hydromechanical amber extraction
E3S Web of Conferences, 2018 The paper represents a process of hydromechanical amber extraction modeling to obtain input data and substantiate operation parameters of mining equipment to develop the improved hydromechanical technique of amber extraction.
Malanchuk Yevhenii +3 more
doaj +1 more source