Results 81 to 90 of about 381,771 (314)

Understanding how junction resistances impact the conduction mechanism in nano-networks

open access: yesNature Communications
Networks of nanowires, nanotubes, and nanosheets are important for many applications in printed electronics. However, the network conductivity and mobility are usually limited by the resistance between the particles, often referred to as the junction ...
Cian Gabbett   +20 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The third version of the AMBER data reduction software

open access: yes, 2010
We present the third release of the AMBER data reduction software by the JMMC. This software is based on core algorithms optimized after several years of operation.
Altariba, Evelyne   +9 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

New records of mosses from Dominican amber [PDF]

open access: yes, 2004
The widespread neotropical moss Calyptothecium duplicatum (Schwägr.) Broth. is reported for a fourth time from Dominican amber. Acroporiites longirostris J.-P. Frahm spec. nov.
Frahm, Jan-Peter
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

21st-century scholarship and Wikipedia [PDF]

open access: yes, 2012
Wikipedia, the world’s fifth most-used Web site, is a good illustration of the growing credibility of online resources. In his article in Ariadne earlier this year, “Wikipedia: Reflections on Use and Academic Acceptance”, Brian Whalley described the ...
Thomas, Amber
core  

Macrostructure and microstructure in narratives of Spanish/English bilingual children with and without language impairment (LI) [PDF]

open access: yes, 2018
There is limited research on character mention and noun phrase elaboration in the narratives of Spanish-English kindergarten and first graders. The current study was designed to determine whether typically developing (TD) Spanish- English bilingual ...
Stansbury, Amber Jean
core   +1 more source

Problembasiert, kompetenzorientiert prüfen

open access: yesZeitschrift für Hochschulentwicklung, 2016
Problembasiertes, kompetenzorientiertes Prüfen fordert von allen Beteiligten den Perspektivenwechsel von der Ziel- zur Kompetenzorientierung. Aufbauend auf Erfahrungen im Projekt „Problembasiert Prüfen“ zeigt dieser Bericht das Vorgehen bei der ...
Monika Urfer-Schumacher
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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