Results 61 to 70 of about 9,902,085 (220)

Polymer‐Grafted Cu(II) Metal–Organic Polyhedra as Scalable, Melt‐Processable Porous Materials

Advanced Science, EarlyView.
The use of a direct synthetic route to obtain polymer‐grafted Cu(II)‐based metal–organic polyhedra gives rise to a low‐cost and scalable cage. This material combines low‐temperature melting, achieving phase changes while preserving cage integrity, and high CO2 uptake exceeding 0.6 mmol g−1.
Alba Cortés‐Martínez, Francisco Sánchez‐Férez, José A. Suárez del Pino, Sergio Royuela, Félix Zamora, Daniel Maspoch, Arnau Carné‐Sánchez   +6 more
wiley   +1 more source

Ambient ionization mass spectrometry: real-time, proximal sample processing and ionization

, 2017
A review of ambient ionization mass spectrometry highlighting the central role of sample preparation immediate to and during sample analysis.
R. Javanshad, A. R. Venter
core   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Sublattice‐Resolved Magnetoelastic Coupling and Opposing Pressure Responses in the Frustrated Magnetocaloric GdMn2O5

Advanced Science, EarlyView.
In GdMn2O5, sublattice‐resolved EXAFS and diffraction analysis reveal pronounced spin‐phonon coupling and an unexpected opposing pressure response: the Mn‐driven Néel temperature slightly decreases while the Gd‐sublattice ordering temperature rises under pressures up to 0.86 GPa.
Romualdo S. Silva Jr., João E. Rodrigues, Javier Gainza, Henrik L. Andersen, Federico Serrano‐Sánchez, Neven Biskup, Olivier Mathon, Norbert M. Nemes, José L. Martínez, José A. Alonso   +9 more
wiley   +1 more source

Relative affinity constants by electrospray ionization and Fourier transform ion cyclotron resonance mass spectrometry: calmodulin binding to peptide analogs of myosin light chain kinase [PDF]

, 2003
Synthetic RS20 peptide and a set of its point-mutated peptide analogs have been used to analyze the interactions between calmodulin (CaM) and the CaM-binding sequence of smooth-muscle myosin light chain kinase both in the presence and the absence of Ca2+.
Lafitte, Daniel, Vainiotalo, Pirjo, Nousiainen, Marjaana, Derrick, Peter J.   +3 more
core   +1 more source

Nonlinear Quantum Effects Drive Grotthuss Proton Conduction in Structured Electrolytes Based on Deep Eutectic Solvents

Advanced Science, EarlyView.
We demonstrate that the inverse relationship between viscosity and conductivity in structured electrolytes can be circumvented by leveraging their hydrogen bonding networks for Grotthuss proton transport. Using a mixture of imidazole and levulinic acid, we show that the existence of extended hydrogen‐bonded chains that can rapidly reorient result in ...
Benworth B. Hansen, Michael S. Chen, Giselle de A. L. e Souza, Kaylie Glynn, Alan Robledo, Emilia Pelegano‐Titmuss, Katherine Hightower, Miguel Muñoz, Rathiesh Pandian, Clemens Burda, Aikaterini Sanida, Mark Dadmun, Burcu E. Gurkan, Steve G. Greenbaum, Mark E. Tuckerman, Joshua R. Sangoro   +15 more
wiley   +1 more source

Self‐Healing Ionogel Dual‐Network Enables Synergistic Defect Passivation and Strain Relief for High‐Efficiency Robust Perovskite Photovoltaics

Advanced Science, EarlyView.
PSCs are afflicted by inherent defects and lattice strain that limit PCE and stability. A cross‐linked multifunctional ionogel [HA‐AA][EMIES] is developed to modulate crystallization, relieve residual strain, and passivate defects, extending carrier diffusion length to over 8 µm and delivering PCEs of 26.45% for rigid devices and 25.14% for flexible ...
Wen Wu, Gang Wang, Chen Liu, Xiao‐Li Du, Sheng Yang, Shao‐Long Wang, Jia‐Yi Tian, Ling‐Feng Chao, Xiang‐Feng Deng, Yi Jiang, Yong‐Hua Chen, Gui‐Chuan Xing, Wen‐Yong Lai   +12 more
wiley   +1 more source

Direct monitoring of drug degradation by easy ambient sonic-spray ionization mass spectrometry: the case of enalapril

, 2015
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Using enalapril maleate as a test case, the ability of ...
Fernandes, R, Amaral, PH, Eberlin, MN, Hoehr, NF   +3 more
core   +1 more source

Metabolic Signatures for Liver Cancer Diagnosis and Mechanistic Insights: A Large‐Scale, Multicenter Study

Advanced Science, EarlyView.
A large‐scale multicenter serum metabolomics study (13 centers, n = 2,149) identified a 9‐metabolite + AFP diagnostic signature for liver cancer (AUC = 0.93). Among the signature, nicotinamide (NAM) was validated as an oncometabolite: NAM enhances NAD+ synthesis, activating SIRT1 to deacetylate and stabilize HIF1α, thereby driving glycolysis, MAPK ...
Yongjie Xu, Jiachen Wang, Chunmeng Ding, Changfa Xia, Yunyong Liu, Yuanjie Zheng, Sheng Chang, Shaokai Zhang, Yutong He, Ruifang Sun, Yunfeng Xi, Yan Liu, Kun Qian, Wanqing Chen   +13 more
wiley   +1 more source

Ambient surface mass spectrometry-ion mobility spectrometry of intact proteins [PDF]

, 2018
Ambient surface mass spectrometry encompasses a broad range of sampling and ionization techniques. To date, only a small subset of these, based on liquid microjunction extraction, have proven suitable for intact protein analysis from thin tissue sections.
Kocurek, Klaudia, Rian L Griffiths, Griffiths, Rian, Cooper, Helen; id_orcid, Helen J Cooper, Klaudia I Kocurek   +5 more
core   +1 more source