Results 51 to 60 of about 412,146 (294)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Single-Frequency GPS/BDS RTK and INS Ambiguity Resolution and Positioning Performance Enhanced with Positional Polynomial Fitting Constraint

Remote Sensing, 2020
Single-frequency GPS/BeiDou navigation satellite system (BDS) real-time kinematic (RTK) and inertial navigation system (INS) integration has wide range of application prospects due to the global deployment of GPS along with the rapid development of BDS ...
Hang Yu, Houzeng Han, Jian Wang, Haiping Xiao, Chuanyang Wang   +4 more
doaj   +1 more source

An Ultra-fast DOA Estimator with Circular Array Interferometer Using Lookup Table Method [PDF]

, 2015
The time-consuming phase ambiguity resolution makes the uniform circular array (UCA) interferometer not suitable for real-time direction-of-arrival (DOA) estimation. This paper introduces the lookup table (LUT) method to solve this problem.
Huang, J. J., Pan, Y. J., Xie, S. Y., Yuan, N. C., Zhang, X. F.   +4 more
core   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The Performance of Three-Frequency GPS PPP-RTK with Partial Ambiguity Resolution

Atmosphere, 2022
The correct ambiguity resolution of real-time kinematic precise point positioning (PPP-RTK) plays an essential role in achieving fast, reliable, and high-precision positioning.
Zhongbao Yan, Xiaohong Zhang
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Ranking-based neural network for ambiguity resolution in ACTS [PDF]

EPJ Web of Conferences
The reconstruction of particle trajectories is a key challenge of particle physics experiments, as it directly impacts particle identification and physics performances while also representing one of the main CPU consumers of many high-energy physics ...
Allaire Corentin, Bouvet Françoise, Grasland Hadrien, Rousseau David   +3 more
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Using a Probabilistic Class-Based Lexicon for Lexical Ambiguity Resolution

, 2000
This paper presents the use of probabilistic class-based lexica for disambiguation in target-word selection. Our method employs minimal but precise contextual information for disambiguation. That is, only information provided by the target-verb, enriched
Prescher, Detlef, Riezler, Stefan, Rooth, Mats   +2 more
core   +5 more sources

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source