Results 191 to 200 of about 8,299 (247)

Investigating drug-liposome interactions using liposomal electrokinetic chromatography. [PDF]

open access: yesAnal Bioanal Chem
Šimonová A   +3 more
europepmc   +1 more source

Antioxidant properties of ambroxol

Free Radical Biology and Medicine, 1994
We tested whether Ambroxol, a drug which stimulates the release of surfactant by pneumocytes type II, may also possess antioxidant properties. To assess the reactivity of Ambroxol with reactive oxygen species, we analysed its ability to decompose hydrogen peroxide (H2O2) and to inhibit the superoxide (O2.-)-dependent autooxidation of pyrogallol ...
Dariusz Nowak   +2 more
exaly   +3 more sources

In vitro and in vivo antioxidant activity of ambroxol

Clinical and Experimental Medicine, 2004
In addition to a mucolytic action, ambroxol has antioxidant and anti-inflammatory properties. The antioxidant effects of ambroxol were studied both in vitro and in vivo. In vitro methods, such as (1) inhibition of hyaluronic acid degradation induced by hydroxy radicals and (2) standard lipid peroxidation assay in rat liver mitochondria and gastric ...
V Stetinova, J Kvetina
exaly   +3 more sources

Effect of Ambroxol of neutrophil chemotaxisin vitro

Agents and Actions, 1988
Ambroxol hydrochloride has been shown to protect the lung from damage by polymorphonuclear leucocyte (PMN). In view of this observation we have studied the effect of Ambroxol on PMN chemotaxis using a variety of chemoattractants. The PMN response was inhibited 50-80% by preincubating the cells with concentrations of 10(-4) M Ambroxol.
D Burnett
exaly   +3 more sources

Ambroxol Is a Scavenger of Hypochlorous Acid and Monochloramine

Pharmacology, 1994
Experimental studies have suggested that ambroxol, a drug clinically used to enhance pulmonary surfactant production, may also exert some anti-inflammatory effects, though specific mechanisms are not yet fully understood. Thus, potential scavenging properties of ambroxol towards the most toxic neutrophil-arising prooxidants hypochlorous acid and ...
LAPENNA, Domenico   +3 more
openaire   +3 more sources

A Controlled Trial of Ambroxol in Chronic Bronchitis

Chest, 1987
Ambroxol is a mucolytic agent which is widely used in chronic bronchitis in Europe. We conducted a double-blind randomized controlled trial of ambroxol vs matched placebo in 90 patients with chronic bronchitis and difficulty clearing secretions. It was concluded that there was no advantage to taking ambroxol.
G H, Guyatt   +3 more
openaire   +2 more sources

Ambroxol-Induced Focal Epileptic Seizure

Clinical Neuropharmacology, 2014
It is well known that in epileptic patients some compounds and different drugs used for the treatment of comorbidities can facilitate or provoke seizures, this evidence regarding a wide spectrum of pharmacological categories. The potential facilitating factors usually include direct toxic effects or pharmacological interactions of either active ...
LAPENTA, Leonardo   +6 more
openaire   +2 more sources

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