Results 11 to 20 of about 1,674 (183)

Safety and efficacy of inhalable ambroxol hydrochloride aerosol for adult patients with respiratory diseases: an open-label, single-arm, multicentre study [PDF]

BMJ Open Respiratory Research
Background Airway mucus hypersecretion is a key pathophysiological feature in many respiratory diseases and could lead to airway obstruction and repeated infections, consequently accelerating disease progression, which impacts on pulmonary function and ...
Jie Zhang, Zhancheng Gao, Xiaohong Chen, Wei Wang, Ting Yang, Gang Chen, Rui Chen, Yi Hu, Xiaohong Yang, Jie Meng, Dan Zhu, Yuanlin Song, Jinping Zheng, Liping Chen, Tianli Wang, Xiaoju Zhang, Xiaoping Ren, Faguang Jin, Zhiyi He, Lin Su, Jinfang Ma, Zhengguang He, Zuke Xiao, Changli Yu, Liangping Mao, Zhenshan Wang, Xianwei Ye, Jianqing Zhao, Keying Xue, Baosong Xie, Ruifeng Zhang, Weiquan Liang, Huili Zhu, Wanjun Yu, Yilan Sun, Shujuan Jiang, Tiantuo Zhang, Gongping Chen   +37 more
doaj   +2 more sources

Determination ambroxole hydrochloride in substance ambroxole hydrochloride and finish medical products by methods adsorption spectroscopy in ultraviolet area, thin layer chromatography and height performers liquid chromatography

Фармацевтичний журнал, 2020
The determination of the qualitative and quantitative content of the main active substance of a microlitic medicinal product is necessary to confirm its good quality.
І. V. Nigencovska, O. V. Burmaka, О. V. Manchenko, К. E. Ziskind   +3 more
doaj   +3 more sources

Efficacy and safety of inhaled ambroxol hydrochloride solution in patients with lower respiratory tract infectious diseases: a randomized, double-blind, placebo-controlled, multicentre clinical trial [PDF]

BMC Infectious Diseases
Background Ambroxol is a widely used mucoactive agent, but the efficacy of inhaled ambroxol in patients with lower respiratory tract infectious (LRTI) disease is poorly understood.
Di Wu, Xiuhua Fu, Faguang Jin, Hui Li, Zhiqiang Qin, Haoyan Wang, Hongmei Yue, Jie Zhang, Zhaolong Cao   +8 more
doaj   +2 more sources

Ambroxol Hydrochloride Loaded Gastro-Retentive Nanosuspension Gels Potentiate Anticancer Activity in Lung Cancer (A549) Cells [PDF]

Gels, 2021
This study aimed to develop gastro-retentive sustained-release ambroxol (ABX) nanosuspensions utilizing ambroxol-kappa-carrageenan (ABX-CRGK) complexation formulations.
Shadab Md, Samaa T. Abdullah, Nabil A. Alhakamy, Ahmad Bani-Jaber, Ammu Kutty Radhakrishnan, Shahid Karim, Naiyer Shahzad, Gamal A. Gabr, Abdulmohsin J. Alamoudi, Waleed Y. Rizg   +9 more
doaj   +2 more sources

Ambroxol hydrochloride as an antibiofilm agent synergizes with tetracycline antibiotics against mature biofilms of multidrug-resistant Klebsiella pneumoniae [PDF]

Biofilm
Multidrug-resistant Klebsiella pneumoniae (MDR-KP) is a major pathogen responsible for hospital-acquired infections, associated with high morbidity and mortality.
TengLi Zhang, XunQin Gao, MengTing Liu, Chun Wen, Peng Jin, Hong Yao, XiWang Liu, YingLan Yu, Hao Shao, Lei Luo   +9 more
doaj   +2 more sources

Beneficial effects of ambroxol hydrochloride on pentylenetetrazol-induced convulsion model in rats

Medicine Science, 2020
In present experimental study, we purposed to research if ambroxol would have beneficial acute effects on PTZ-induced convulsions by EEG records. 48 rats were randomly divided into two groups; group A for EEG recordings and B for behavioral evaluations ...
Eda Sunnetci, Volkan Solmaz, Halil Ugur Hatipoglu, Oytun Erbas   +3 more
doaj   +2 more sources

Ambroxol hydrochloride alleviates acute lung injury induced by gastric juice aspiration in rats [PDF]

Jichu yixue yu linchuang, 2022
Objective To investigate the therapeutic and protective effect of ambroxol hydrochloride on acute lung injury caused by aspiration of gastric juice in rats.
CUI Yi-yao, WANG Feng, LYU Xiao-shuo, LIU Chun-quan, XU Kai-kai, CUI Yong
doaj   +2 more sources

FORMULATION AND STATISTICAL OPTIMIZATION OF BILAYER SUBLINGUAL TABLETS OF LEVOCETIRIZINE HYDROCHLORIDE AND AMBROXOL HYDROCHLORIDE [PDF]

Asian Journal of Pharmaceutical and Clinical Research, 2016
Objective: The aim of the present study is to formulate and optimize bilayer sublingual tablets of Levocetrizine hydrochloride and Ambroxolhydrochloride using a 23 response surface methodology employing design expert-10.0.
Choudhury, Priyanka, Dash, Suvakanta, Deb, Pulak   +2 more
core   +4 more sources

Comparison of Jinzhen oral liquid and ambroxol hydrochloride and clenbuterol hydrochloride oral solution in the treatment of acute bronchitis in children: A multicenter, non-inferiority, prospective, randomized controlled trial [PDF]

Acta Pharmaceutica Sinica B
The comparison between traditional Chinese medicine Jinzhen oral liquid (JZOL) and Western medicine in treating children with acute bronchitis (AB) showed encouraging outcomes.
Qinhua Fan, Chongming Wu, Yawei Du, Boyang Wang, Yanming Xie, Zeling Zhang, Wenquan Su, Zizhuo Wang, Changchang Xu, Xueke Li, Ying Ding, Xinjiang An, Jing Chen, Yunying Xiao, Rong Yu, Nan Li, Juan Wang, Yiqun Teng, Hongfen Lv, Nian Yang, Yuling Wen, Xiaoli Huang, Wei Pan, Yufeng Liu, Xueqin Xi, Qianye Zhao, Changshan Liu, Jian Xu, Haitao Zhang, Lie Zhuo, Qiangquan Rong, Yu Xia, Qin Shen, Shao Li, Junhong Wang, Shengxian Wu   +35 more
doaj   +2 more sources

Beyond Use Date (BUD) Determination of Ambroxol Hydrochloride Syrup by High-Performance Liquid Chromatography – UV/VIS Detector [PDF]

Pharmaceutical Sciences and Research, 2023
Ambroxol HCl is a mucolytic agent often used to treat respiratory disorders associated with excess mucus secretion. This study aims to determine the beyond-use date (BUD) of ambroxol HCl syrup on the market based on analysis of the decrease in drug ...
Catur Jatmika, Raditya Iswandana, Indah Dewi Lestari   +2 more
doaj   +3 more sources