Rational mucolytic therapy with ambroxol: controversial and indisputable. A review [PDF]
Consilium Medicum, 2023 Many years of experience in the use of ambroxol is based on its ability to regulate the basic mechanisms of physiological production and transport of bronchial mucus.
Sergey L. Babak +2 more
doaj +2 more sources
CNS Neuroscience and Therapeutics, 2008 For almost three decades ambroxol has been used in the therapy of airway diseases. In 2002, ambroxol lozenges were marketed for the treatment of sore throat making use of its local anesthetic effect. Detailed investigations of ambroxol with modern pharmacological methods yielded additional interesting results: ambroxol has been found to have profound ...
Thomas Weiser
exaly +3 more sources
Therapeutic Potential of Ambroxol in Osteoarthritis: A Drug Repurposing Study [PDF]
PharmaceuticalsBackground/Objectives: Ambroxol is a mucolytic agent widely used in the treatment of respiratory diseases; however, evidence in the literature indicates anti-inflammatory, analgesic, and immunomodulatory properties, suggesting potential for therapeutic ...
Michelline Joana Tenório Albuquerque Madruga Mesquita +15 more
doaj +2 more sources
Efficacy and safety of inhaled ambroxol hydrochloride solution in patients with lower respiratory tract infectious diseases: a randomized, double-blind, placebo-controlled, multicentre clinical trial [PDF]
BMC Infectious DiseasesBackground Ambroxol is a widely used mucoactive agent, but the efficacy of inhaled ambroxol in patients with lower respiratory tract infectious (LRTI) disease is poorly understood.
Di Wu +8 more
doaj +2 more sources
Safety and Efficacy of Ambroxol Therapy in Polish Patients with Gaucher Disease [PDF]
LifeBackground: Gaucher disease (GD) is a lysosomal storage disorder caused by deficiency of β-glucocerebrosidase, leading to accumulation of glucocerebroside in lysosomes.
Patryk Lipiński +11 more
doaj +2 more sources
Efficacy and safety of inhaled ambroxol solution in improving sputum of lower respiratory tract infection in children: a multicenter, randomized, double-blind, placebo-controlled trial [PDF]
BMC Pulmonary MedicineObjective To evaluate the efficacy and safety of inhaled ambroxol solution in improving sputum of lower respiratory tract infections (LRTIs) in children.
Baoping Xu +9 more
doaj +2 more sources
Ambroxol confers neuroprotection against scopolamine-induced Alzheimer’s-like pathology by modulating oxidative stress, neuroinflammation, and cognitive deficits via Nrf-2/JNK/GSK-3β signaling pathways [PDF]
Frontiers in Aging NeuroscienceAlzheimer’s disease (AD) is the most common and costly chronic progressive neurodegenerative disorder, with the highest impact on public health worldwide.
Waqas Ahmad +6 more
doaj +2 more sources
Frontiers in Microbiology, 2022 Ambroxol is a commonly used mucolytic agent principally used to treat respiratory diseases, which may have a role as adjunctive therapy for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, but there is lack of evidence about its ...
Yun Lu +13 more
doaj +1 more source
Pharmaceutical Sciences and Research, 2023 Ambroxol HCl is a mucolytic agent often used to treat respiratory disorders associated with excess mucus secretion. This study aims to determine the beyond-use date (BUD) of ambroxol HCl syrup on the market based on analysis of the decrease in drug ...
Catur Jatmika +2 more
doaj +1 more source
Фармацевтичний журнал, 2020 The determination of the qualitative and quantitative content of the main active substance of a microlitic medicinal product is necessary to confirm its good quality.
І. V. Nigencovska +3 more
doaj +1 more source