Results 11 to 20 of about 3,769 (208)
Beneficial effects of ambroxol hydrochloride on pentylenetetrazol-induced convulsion model in rats
In present experimental study, we purposed to research if ambroxol would have beneficial acute effects on PTZ-induced convulsions by EEG records. 48 rats were randomly divided into two groups; group A for EEG recordings and B for behavioral evaluations ...
Eda Sunnetci +3 more
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VALIDATION METHOD OF ULTRAVIOLET SPECTROPHOTOMETRY DETERMINATION OF CONTENT IN AMBROXOL HCl TABLET [PDF]
Ambroxol Hydrochloride (Ambroxol HCI) is one of mucolytic drugs that is commonly used to dilute thesecretion within the respiratory tract. This process is completed by lowering the viscosity of mucopolysaccharides, in which its characteristic which is ...
Tedy Kurniawan Bakri +3 more
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This article reviews the literature on the development of biofilms on airway in respiratory diseases and the impact of ambroxol on them. Since biofilm infections respond poorly to standard antibiotic therapy, their treatment is a serious challenge in the
Yu.V. Marushko, T.V. Hyshchak
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Heterozygous mutations in GBA1 gene, encoding for lysosomal enzyme glucocerebrosidase (GCase), are a major risk factor for sporadic Parkinson's disease (PD).
Giulia Ambrosi +5 more
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Neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), are multifactorial. Among various factors, lipopolysaccharides (LPSs) from Gram-negative bacteria, such as E.
Safi Ullah +10 more
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Ambroxol for the treatment of fibromyalgia: science or fiction? [PDF]
Kai-Uwe Kern, Myriam Schwickert Institute of Pain Medicine/Pain Practice, Wiesbaden, Germany Abstract: Fibromyalgia appears to present in subgroups with regard to biological pain induction, with primarily inflammatory, neuropathic/neurodegenerative ...
Kern KU, Schwickert M
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Analysis of Solubility, pH, Antimicrobial Action and Cytotoxicity of Calcium Hydroxide Paste Associated With Ambroxol Hydrochloride. [PDF]
ABSTRACT This study evaluated the association of ambroxol hydrochloride with calcium hydroxide paste as intracanal medication to enhance antimicrobial action on biofilm without affecting pH, solubility and cytotoxicity. Calcium hydroxide (CH) paste and formulations with different ambroxol concentrations were placed into artificial teeth conditioned in ...
Mota TFR +6 more
europepmc +2 more sources
Non-Pulmonary Mechanisms of Action of Ambroxol in In Vivo Experimental Models: a Systematic Review. [PDF]
ABSTRACT Background Repositioning offers a cost‐effective approach to discovering new therapeutic applications for existing medications. Ambroxol, primarily used as a mucolytic for respiratory diseases, has demonstrated anti‐inflammatory, analgesic, and antioxidant properties, suggesting potential benefits in non‐pulmonary conditions.
Mesquita MJTAM +13 more
europepmc +2 more sources
Ambroxol: A potential therapeutics against neurodegeneration
Ambroxol hydrochloride is a pharmacological chaperone approved by FDA as an expectorant. Currently, it is used as an antitussive and anti-asthmatic agent.
Prajwal Dhanve +4 more
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Ambroxol therapy for Parkinson’s disease: Systematic literature review [PDF]
Parkinson’s disease (PD) is the second most common neurodegenerative disease. The accumulation of α-synuclein protein in the basal ganglia is the underlying pathogenesis of PD. Genetic abnormalities are one of the predisposing factors for PD.
Virgi Mayang Maharani +3 more
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