Results 11 to 20 of about 3,769 (208)

Beneficial effects of ambroxol hydrochloride on pentylenetetrazol-induced convulsion model in rats

open access: yesMedicine Science, 2020
In present experimental study, we purposed to research if ambroxol would have beneficial acute effects on PTZ-induced convulsions by EEG records. 48 rats were randomly divided into two groups; group A for EEG recordings and B for behavioral evaluations ...
Eda Sunnetci   +3 more
doaj   +2 more sources

VALIDATION METHOD OF ULTRAVIOLET SPECTROPHOTOMETRY DETERMINATION OF CONTENT IN AMBROXOL HCl TABLET [PDF]

open access: yesJurnal Natural, 2015
Ambroxol Hydrochloride (Ambroxol HCI) is one of mucolytic drugs that is commonly used to dilute thesecretion within the respiratory tract. This process is completed by lowering the viscosity of mucopolysaccharides, in which its characteristic which is ...
Tedy Kurniawan Bakri   +3 more
doaj   +5 more sources

Biofilm The Formation in Respiratory Diseases. Influence of Ambroxol on Airway Biofilms (Literature Review)

open access: yesZdorovʹe Rebenka, 2016
This article reviews the literature on the development of biofilms on airway in respiratory diseases and the impact of ambroxol on them. Since biofilm infections respond poorly to standard antibiotic therapy, their treatment is a serious challenge in the
Yu.V. Marushko, T.V. Hyshchak
doaj   +2 more sources

Ambroxol-induced rescue of defective glucocerebrosidase is associated with increased LIMP-2 and saposin C levels in GBA1 mutant Parkinson's disease cells

open access: yesNeurobiology of Disease, 2015
Heterozygous mutations in GBA1 gene, encoding for lysosomal enzyme glucocerebrosidase (GCase), are a major risk factor for sporadic Parkinson's disease (PD).
Giulia Ambrosi   +5 more
doaj   +2 more sources

Ambroxol attenuates detrimental effect of LPS-induced glia-mediated neuroinflammation, oxidative stress, and cognitive dysfunction in mice brain

open access: yesFrontiers in Immunology
Neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), are multifactorial. Among various factors, lipopolysaccharides (LPSs) from Gram-negative bacteria, such as E.
Safi Ullah   +10 more
doaj   +2 more sources

Ambroxol for the treatment of fibromyalgia: science or fiction? [PDF]

open access: yesJournal of Pain Research, 2017
Kai-Uwe Kern, Myriam Schwickert Institute of Pain Medicine/Pain Practice, Wiesbaden, Germany Abstract: Fibromyalgia appears to present in subgroups with regard to biological pain induction, with primarily inflammatory, neuropathic/neurodegenerative ...
Kern KU, Schwickert M
doaj   +2 more sources

Analysis of Solubility, pH, Antimicrobial Action and Cytotoxicity of Calcium Hydroxide Paste Associated With Ambroxol Hydrochloride. [PDF]

open access: yesAust Endod J
ABSTRACT This study evaluated the association of ambroxol hydrochloride with calcium hydroxide paste as intracanal medication to enhance antimicrobial action on biofilm without affecting pH, solubility and cytotoxicity. Calcium hydroxide (CH) paste and formulations with different ambroxol concentrations were placed into artificial teeth conditioned in ...
Mota TFR   +6 more
europepmc   +2 more sources

Non-Pulmonary Mechanisms of Action of Ambroxol in In Vivo Experimental Models: a Systematic Review. [PDF]

open access: yesFundam Clin Pharmacol
ABSTRACT Background Repositioning offers a cost‐effective approach to discovering new therapeutic applications for existing medications. Ambroxol, primarily used as a mucolytic for respiratory diseases, has demonstrated anti‐inflammatory, analgesic, and antioxidant properties, suggesting potential benefits in non‐pulmonary conditions.
Mesquita MJTAM   +13 more
europepmc   +2 more sources

Ambroxol: A potential therapeutics against neurodegeneration

open access: yesHealth Sciences Review, 2023
Ambroxol hydrochloride is a pharmacological chaperone approved by FDA as an expectorant. Currently, it is used as an antitussive and anti-asthmatic agent.
Prajwal Dhanve   +4 more
doaj   +1 more source

Ambroxol therapy for Parkinson’s disease: Systematic literature review [PDF]

open access: yesRomanian Journal of Neurology, 2023
Parkinson’s disease (PD) is the second most common neurodegenerative disease. The accumulation of α-synuclein protein in the basal ganglia is the underlying pathogenesis of PD. Genetic abnormalities are one of the predisposing factors for PD.
Virgi Mayang Maharani   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy