Possibility for the use of bromhexine to prevent infection with SARS-CoV-2 [PDF]
The routine use of bromhexine to prevent infection SARS-CoV-2 is not recommended. The use of bromhexine is possible in clinical trials.
K. A. Zagorodnikova +2 more
doaj +2 more sources
Effect of bromhexine on clinical outcomes and mortality in COVID-19 patients: A randomized clinical trial [PDF]
Introduction: Bromhexine is a potential therapeutic option in COVID-19, but no data from a randomized clinical trial has been available. The present study aimed to evaluate the efficacy of bromhexine in intensive care unit (ICU) admission, mechanical ...
Khalil Ansarin +10 more
doaj +3 more sources
Pharmacoeconomic analysis of bromhexine for prophylactic of influenza A and B [PDF]
The aim of the present analysis is to assess the cost-effectiveness of influenza A and B prophylaxis with bromhexine, used off-label, for the purposes of the healthcare system in Bulgaria.
Guenka Petrova, Vanyo Mitev
doaj +4 more sources
Comparison of treatment of COVID-19 with inhaled bromhexine, higher doses of colchicine and hymecromone with WHO-recommended paxlovid, molnupiravir, remdesivir, anti-IL-6 receptor antibodies and baricitinib [PDF]
Millions of publications and thousands of clinical trials have not led to the discovery of an effective treatment for COVID-19. We believe that the reason for this is the inaccurate strategy of inhibiting target molecules involved in the pathogenesis of ...
Vanyo Mitev
doaj +4 more sources
Bromhexine is a potential drug for COVID-19; From hypothesis to clinical trials
COVID-19 (novel coronavirus disease 2019), caused by the SARS-CoV-2 virus, has various clinical manifestations and several pathogenic pathways. Although several therapeutic options have been used to control COVID-19, none of these medications have been ...
S. Bahadoram +6 more
doaj +1 more source
Spectrophotometric Determination of Bromhexine Hydrochloride by Azo-Dye Formation Reaction [PDF]
A spectrophotometric method for the assay of trace amounts of bromhexine-HCl based on the reaction of bromhexine-HCl with nitrite ion to form the corresponding diazonium salt followed by coupling reaction with pyrogallol in a acidic medium to form a ...
Nabeel Othman, Shilan Omer
doaj +1 more source
The place of combined mucoactive drugs in the treatment of acute respiratory infections in children
The problem of respiratory diseases and their therapy options still retains much of its urgency. Respiratory diseases in children are still super common.
L. S. Starostina
doaj +1 more source
Computational Identification of a Putative Allosteric Binding Pocket in TMPRSS2
Camostat, nafamostat, and bromhexine are inhibitors of the transmembrane serine protease TMPRSS2. The inhibition of TMPRSS2 has been shown to prevent the viral infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other viruses ...
Jacopo Sgrignani +2 more
doaj +1 more source
Acute interstitial nephritis observed with three different triggering agents
A 70‐year‐old female patient developed acute interstitial nephritis (AIN) after treatment with non‐steroidal anti‐inflammatory drugs (NSAIDs), proton pump inhibitors (PPI), and Bromhexine. Renal biopsy confirmed the diagnosis, and the patient was treated
Niloofar Nobakht +7 more
doaj +1 more source
Aim. To evaluate the efficacy and safety of a combination drug containing ambroxol, guaifenesin, and levosalbutamol, oral solution, versus Ascoril Expectorant, syrup (combination of bromhexine, guaifenesin, and salbutamol) in the treatment of productive ...
Andrey A. Zaitsev +3 more
doaj +1 more source

