Research Note: Pharmacokinetics of Bromhexine Hydrochloride in Broilers After Single Oral and Intravenous Administration [PDF]
Poultry Science: The current study aimed to investigate the pharmacokinetics of bromhexine hydrochloride in broilers after single intravenous (IV) and oral (PO) administration at 2.5 mg/kg body weight (BW).
Xing-Ping Li, Fan Yang, Ming-Hui Duan
exaly +6 more sources
Application of Hydrophilic Polymers to the Preparation of Prolonged-Release Minitablets With Bromhexine Hydrochloride and Bisoprolol Fumarate [PDF]
PharmaceuticsMinitablets have been extensively studied in recent years as a convenient pediatric form because they allow successful administration even in very young children.
Aleksander Mendyk +2 more
exaly +7 more sources
Bromhexine Hydrochloride Prophylaxis of COVID-19 for Medical Personnel: A Randomized Open-Label Study [PDF]
Interdisciplinary Perspectives on Infectious Diseases, 2022 Background. Bromhexine hydrochloride has been suggested as a TMPRSS2 protease blocker that precludes the penetration of SARS-CoV-2 into cells. We aimed to assess the preventive potential of regular bromhexine hydrochloride intake for COVID-19 risk ...
Evgeny N. Mikhaylov +7 more
doaj +3 more sources
COVID‐19 Prophylactic Effect of Bromhexine Hydrochloride [PDF]
Immunity, Inflammation and DiseaseIntroduction Despite extensive efforts to identify effective treatments for COVID‐19, preventive strategies remain essential. Bromhexine hydrochloride (BRH), an over‐the‐counter mucolytic with potential TMPRSS2 inhibition, may reduce viral entry and thus
Vanyo Mitev +4 more
doaj +3 more sources
Development and validation of a green analytical method to determine bromhexine hydrochloride in pharmaceuticals [PDF]
Scientific ReportsErythrosine B (EB) is a food colorant and antiviral xanthene dye that is widely used as a color additive in pharmaceutical and cosmetic industries. Its application as a sensor for spectrophotometric measurement of amine-based pharmaceuticals offers ...
Salwa Kh. Mohamed +2 more
doaj +4 more sources
Tissue Distribution of Bromhexine Hydrochloride in Broiler Chickens Following Oral Administration via Drinking Water [PDF]
Poultry ScienceThis study aimed to investigate the tissue distribution of bromhexine hydrochloride in broiler chickens following oral administration via drinking water.
Xing-Ping Li, Fan Yang, Ming-Hui Duan
exaly +4 more sources
Structural insights and inhibition mechanism of TMPRSS2 by experimentally known inhibitors Camostat mesylate, Nafamostat and Bromhexine hydrochloride to control SARS-coronavirus-2: A molecular modeling approach [PDF]
Informatics in Medicine Unlocked, 2021 Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been responsible for the cause of global pandemic Covid-19 and to date, there is no effective treatment available.
Kailas D. Sonawane +11 more
doaj +2 more sources
Bromhexine Hydrochloride Prophylaxis of COVID-19 for Medical Personnel: A Randomized Open-Label Study [PDF]
Interdisciplinary Perspectives on Infectious Diseases, 2021 Background: Bromhexine hydrochloride has been suggested as a TMPRSS2 protease blocker that precludes the penetration of SARS-CoV-2 into cells. We aimed to assess the preventive potential of regular bromhexine hydrochloride intake for COVID-19 risk reduction in medical staff actively involved in the evaluation and treatment of ...
Mikhaylov EN +7 more
europepmc +4 more sources
Spectrophotometric Determination of Bromhexine Hydrochloride by Azo-Dye Formation Reaction [PDF]
مجلة التربية والعلم, 2009 A spectrophotometric method for the assay of trace amounts of bromhexine-HCl based on the reaction of bromhexine-HCl with nitrite ion to form the corresponding diazonium salt followed by coupling reaction with pyrogallol in a acidic medium to form a ...
Nabeel Othman, Shilan Omer
doaj +2 more sources
Investigating the Impact of Co-processed Excipients on the Formulation of Bromhexine Hydrochloride Orally Disintegrating Tablets (ODTs). [PDF]
Pharm Res, 2023 Abstract Purpose Orodispersible tablets (orally disintegrating tablets, ODTs) have been used in pharmacotherapy for over 20 years since they overcome the problems with swallowing solid dosage forms. The successful formula manufactured by direct compression shall ensure acceptable mechanical strength and short ...
Woyna-Orlewicz K +11 more
europepmc +4 more sources