Results 31 to 40 of about 555 (124)

Care of older people and people requiring palliative care with COVID‐19: guidance from the Australian National COVID‐19 Clinical Evidence Taskforce

Medical Journal of Australia, Volume 216, Issue 4, Page 203-208, March 2022., 2022
Abstract Introduction Older people living with frailty and/or cognitive impairment who have coronavirus disease 2019 (COVID‐19) experience higher rates of critical illness. There are also people who become critically ill with COVID‐19 for whom a decision is made to take a palliative approach to their care.
Saskia Cheyne, Richard I Lindley, Natasha Smallwood, Britta Tendal, Michael Chapman, David Fraile Navarro, Phillip D Good, Peter Jenkin, Steve McDonald, Deidre Morgan, Melissa Murano, Tanya Millard, Vasi Naganathan, Velandai Srikanth, Penelope Tuffin, Joshua Vogel, Heath White, Samantha P Chakraborty, Elizabeth Whiting, Leeroy William, Patsy M Yates, Mandy Callary, Julian Elliott, Meera R Agar, for the National COVID‐19 Clinical Evidence Taskforce   +24 more
wiley   +1 more source

Acute interstitial nephritis observed with three different triggering agents

Clinical Case Reports, Volume 10, Issue 3, March 2022., 2022
Several drugs can cause allergic interstitial nephritis (AIN) including over the counter agents. Bromhexine an over the counter cough remedies can be associated with AIN. The timing of treatment initiation with steroid is critical to decrease risk of fibrosis and future chronic kidney disease and loss of GFR.
Niloofar Nobakht, Ramy M. Hanna, Mohammad Kamgar, John Sinclair, Lewis Simon, Sina Emami, Anthony Sisk, Anjay Rastogi   +7 more
wiley   +1 more source

Effects of Prone Positioning for Patients with Acute Respiratory Distress Syndrome Caused by Pulmonary Contusion: A Single‐Center Retrospective Study

Canadian Respiratory Journal, Volume 2022, Issue 1, 2022., 2022
Background. The effects of prone positioning (PP) on patients with acute respiratory distress syndrome (ARDS) caused by pulmonary contusion (PC) are unclear. We sought to determine the efficacy of PP among patients whose ARDS was caused by PC. Methods.
Xiaoyi Liu, Hui Liu, Shilian Liu, Wenlai Zhou, Qing Lan, Jun Duan, Xue Li, Xiangde Zheng, Alice M. Turner   +8 more
wiley   +1 more source

Spectrophotometric Assay of Bromhexine hydrochloride in Pure and in Pharmaceutical Dosage Forms by Diazometry Coupling Reaction [PDF]

مجلة التربية والعلم, 2013
Asimple, accurate and sensitive spectrophotometric method has been developed for quantitative determination of bromhexine hydrochloride (BH) in both pure form and in its pharmaceutical preparations. The proposed method is based on the diazotization of BH
Salim Mohammed, Rana Almukhtar
doaj   +1 more source

Evaluating the efficacy and safety of bromhexine hydrochloride tablets in treating pediatric COVID-19 [PDF]

Medicine, 2020
Wang, Yuying, Zhang, Yinghua, Chen, Xia, Xue, Kun, Zhang, Tianjing, Ren, Xiaohong   +5 more
openaire   +2 more sources

Targeting host cell proteases as a potential treatment strategy to limit the spread of SARS‐CoV‐2 in the respiratory tract

Pharmacology Research &Perspectives, Volume 9, Issue 1, February 2021., 2021
All elements used in the illustration were obtained from the Reactome icon library (https://reactome.org/icon‐lib). The representative 3D structures of host cell proteases and human ACE2 were obtained from Protein Data Bank (https://www.rcsb.org/). Drug tablet/capsule icons come from www.iconscout.com.
Ismail A. El‐Shimy, Mahmoud M. A. Mohamed, Syed Shahzad Hasan, Muhammad A. Hadi   +3 more
wiley   +1 more source

A Review on Expression, Pathological Roles, and Inhibition of TMPRSS2, the Serine Protease Responsible for SARS‐CoV‐2 Spike Protein Activation

Scientifica, Volume 2021, Issue 1, 2021., 2021
SARS‐CoV‐2, the coronavirus responsible for the COVID‐19 pandemic, uses the host cell membrane receptor angiotensin‐converting enzyme 2 (ACE2) for anchoring its spike protein, and the subsequent membrane fusion process is facilitated by host membrane proteases.
Jyotirmoy Sarker, Pritha Das, Sabarni Sarker, Apurba Kumar Roy, A. Z. M. Ruhul Momen, S.Y. Seong   +5 more
wiley   +1 more source

Efficacy and Safety of Dahuang Zhechong Pill in Silicosis: A Randomized Controlled Trial

Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
Background. There is no effective therapy for silicosis, and Dahuang Zhechong pill (DHZCP), an ancient Chinese medicine prescription, may have a therapeutic effect on silicosis. This study aims to verify the efficacy and safety of DHZCP in silicosis. Methods.
Wu-Yi-Nuo Tang, Jing-Tao Liang, Ju Wu, Li Liu, Ming-Zhang Lu, Xiao-Yan He, Li-Juan Wu, Huan-Yu Jiang, Fei Wang, Xiao Meng, Shun-Pin Li, Guoqiang Xing   +11 more
wiley   +1 more source

Drug Repurposing Approach, Potential Drugs, and Novel Drug Targets for COVID‐19 Treatment

Journal of Environmental and Public Health, Volume 2021, Issue 1, 2021., 2021
Novel coronavirus first appeared in Wuhan, China, in December 2019, and it speedily expanded globally. Some medications which are used to treat other diseases seem to be effective in treating COVID‐19 even without explicit support. The existing drugs that are summarized in this review primarily focused on therapeutic agents that possessed activity ...
Zemene Demelash Kifle, Akeberegn Gorems Ayele, Engidaw Fentahun Enyew, Felix Broecker   +3 more
wiley   +1 more source

Spectrophotometric Determination of Bromhexine Hydrochloride in Pharmaceutical Preparations

Journal of AOAC INTERNATIONAL, 1984
Abstract The presence of an aromatic primary amino group in bromhexine HCI enables the use of diazotization-coupling, according to the classic Bratton-Marshall method, for its analysis in pharmaceutical preparations. Spectrophotometric parameters were established for standardization of the method, including statistical analysis of data ...
M I, Santoro, M M, dos Santos, J F, Magalhães   +2 more
openaire   +2 more sources